Understanding asthma in older people

• Register: ANZCTR
• Last refreshed on: 22 February 2013
• Main ID: ACTRN12610000225011
• Date of registration: 17/03/2010
• Primary sponsor: Charities/Societies/Foundations Woolcock Institute of Medical Research
• Public title: Understanding asthma in older people
• Scientific title: Is asthma in the elderly a disease of the peripheral airways? An observational study measuring airway hyperresponsiveness
• Date of first enrolment: 1/04/2010
• Target sample size: 100
• Recruitment status: Not yet recruiting
• URL: http://www.anzctr.org.au/ACTRN12610000225011.aspx
• Study type: Observational

Countries of recruitment

Australia

Contacts

• Name: Dr Greg King

• Name: Dr Greg King

Key inclusion & exclusion criteria

Inclusion criteria: Doctor diagnosed asthmatics
Exclusion criteria: Current smoking or history of smoking > 10 pack years, lung disease other than asthma, taking oral corticosteroids in last 4 weeks or having upper respiratory tract infection in last 4 weeks.

Age minimum: 18 Years
Age maximum: 100 Years
Gender: Both males and females

Health Condition(s) or Problem(s) studied

Asthma

Intervention(s)

The predictors of airway hyperresponsiveness are being measured and compared with other measures of ventilation heterogeneity, lung elastic recoil, airway closure measured by lung imaging and lung volumes.
The study will last for 3 years, however each subject will complete 4 visits over 1-2 weeks.

Primary Outcome(s)

Airway hyperresponsiveness meaured using methacholine challenge

Secondary Outcome(s)

Nil

Secondary ID(s)

None

Source(s) of Monetary Support

National Health and Medical Research Council

Secondary Sponsor(s)

Dept of Respiratory Medicine, Royal North Shore Hospital