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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ANZCTR |
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Last refreshed on:
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22 February 2013 |
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Main ID: |
ACTRN12606000006549 |
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Date of registration:
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04/01/2006 |
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Primary sponsor: |
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Public title:
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The effect of serotonin receptor antagonists on delirium after coronary artery bypass graft surgery.
SERIOUS-D: Serotonin Receptor Inhibition OUtcome after Surgery- Delirium |
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Scientific title:
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The effect of serotonin receptor antagonists on delirium after coronary artery bypass graft surgery. |
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Date of first enrolment:
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1/06/2006 |
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Target sample size:
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100 |
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Recruitment status: |
Not yet recruiting |
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URL:
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http://www.anzctr.org.au/ACTRN12606000006549.aspx |
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Study type:
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Interventional |
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Study design:
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Randomised controlled trial
Parallel |
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Countries of recruitment
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Australia
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Contacts
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Name:
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Dr Bradley La Ferlita |
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Address:
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c/o Department of Anaesthesia
St Vincent''s Hospital
Victoria Pde
Fitzroy VIC 3065, Australia
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Telephone:
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+61 3 92882211 |
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Email:
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bradley.laferlita@svhm.org.au |
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Affiliation:
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Name:
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Dr Bradley La Ferlita |
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Address:
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c/o Department of Anaesthesia
St Vincent''s Hospital
Victoria Pde
Fitzroy VIC 3065, Australia
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Telephone:
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+61 3 92882211 |
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Email:
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bradley.laferlita@svhm.org.au |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: All patients undergoing coronary artery bypass graft (CABG) surgery, requiring cardiopulmonary bypass (CPB).
Exclusion criteria: Pre-existing delirium, drug/alcohol abuse, age<60 years, haemodynamic instability pre-operatively, acute or evolving myocardial ischaemia.
Age minimum:
60 Years
Age maximum:
0 Not stated
Gender:
Both males and females
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Health Condition(s) or Problem(s) studied
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Post cardiac bypass delirium
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Intervention(s)
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Participants will receive tropisetron in the first 5 post-operative days.
Investigating the use of tropisetron vs placebo on the incidence of post-cardiopulmonary bypass related delirium in the first 5 post-operative days. A pilot study of 100 patients in the early post-operative phase.
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Primary Outcome(s)
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Post-cardiopulmonary bypass related delirium
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Secondary Outcome(s)
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Cardiovascular support
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Hospital length of stay.
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Intensive care unit length of stay
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Source(s) of Monetary Support
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St Vincent's Hospital, Melbourne
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