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Register:	ClinicalTrials.gov
Last refreshed on:	12 December 2020
Main ID:	NCT02833467
Date of registration:	09/07/2016
Prospective Registration:	No
Primary sponsor:	Peking University People's Hospital
Public title:	Identifying Genomic Mutations of Multiple Primary Lung Cancers by Circulating Tumor DNA
Scientific title:	A Prospective Study of Identifying Genomic Mutations of Multiple Primary Lung Cancers by Circulating Tumor DNA
Date of first enrolment:	January 2015
Target sample size:	45
Recruitment status:	Active, not recruiting
URL:	https://clinicaltrials.gov/show/NCT02833467
Study type:	Observational
Study design:
Phase:

Countries of recruitment

Contacts

Name:	Kezhong Chen, M.D.
Address:
Telephone:
Email:
Affiliation:	Peking University People's Hospital

Name:	Jun Wang, M.D.
Address:
Telephone:
Email:
Affiliation:	Peking University People's Hospital

Key inclusion & exclusion criteria

Inclusion Criteria:

- Patients must have given written informed consent

- Histopathologically confirmed NSCLC

- Considered multiple or multifocal primary lung cancer by clinical criteria

Exclusion Criteria:

- Malignant tumor history within the past 5 years

- Patients who received any treatment prior to resection

- Insufficient tumor tissue or blood sample

Age minimum: 18 Years
Age maximum: N/A
Gender: All

Health Condition(s) or Problem(s) studied

Carcinoma

Thoracic Neoplasms

Non-small-cell Lung Cancer

Intervention(s)

Primary Outcome(s)

The detection rate of cancer related genes in multiple primary lung cancer patients by targeted next generation sequencing [Time Frame: 18 months]

Secondary Outcome(s)

The concordant and discordant frequency of genomic results between tumor tissue and circulating tumor DNA in multiple primary lung cancer patients [Time Frame: 18 months]

The relationship between disease free survival and genomic results in multiple primary lung cancer patients [Time Frame: 5 years]

The relationship between overall survival and genomic results in multiple primary lung cancer patients [Time Frame: 5 years]

Secondary ID(s)

PTHO1502

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Secondary Sponsor(s)

San Valley Biotechnology Incorporated

Ethics review

Results

Results available:
Date Posted:
Date Completed:
URL:

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