Myocardial Injury in Remifentanil-based Versus Sevoflurane-sufentanil Balanced Regimens in OPCAB Surgery

• Register: ClinicalTrials.gov
• Last refreshed on: 3 August 2015
• Main ID: NCT02499445
• Date of registration: 05/03/2015
• Prospective Registration: No
• Primary sponsor: Konkuk University Medical Center
• Public title: Myocardial Injury in Remifentanil-based Versus Sevoflurane-sufentanil Balanced Regimens in OPCAB Surgery
• Scientific title: Comparisons of Myocardial Injury After Using Different Anesthetics Regimens for Off-pump Coronary Artery Bypass Surgery: Remifentanil-based Versus Sevoflurane-sufentanil Balanced Regimen
• Date of first enrolment: November 2007
• Target sample size: 120
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT02499445
• Study type: Interventional
• Study design: Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
• Phase: N/A

Countries of recruitment

Korea, Republic of

Key inclusion & exclusion criteria

Inclusion Criteria:

- patient undergoing OPCAB surgery

- patient signed written informed consent

Exclusion Criteria:

- patient with Intra-aortic balloon pump

- patient with renal replacement therapy

- patient wants to withdraw the participation to the study



Age minimum: 19 Years
Age maximum: 72 Years
Gender: Both

Health Condition(s) or Problem(s) studied

Ischemic Heart Disease

Intervention(s)

Drug: sufentanil

Drug: propofol

Drug: sevoflurane 2

Drug: sevoflurane 1

Drug: Remifentanil

Primary Outcome(s)

troponin I [Time Frame: one day after surgery]

Secondary Outcome(s)

creatinin kinase-MB [Time Frame: one day after surgery]

Secondary ID(s)

KUH1160004

Source(s) of Monetary Support

Please refer to primary and secondary sponsors