Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
Register:
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ClinicalTrials.gov |
Last refreshed on:
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19 February 2015 |
Main ID: |
NCT02190773 |
Date of registration:
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08/07/2014 |
Prospective Registration:
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No |
Primary sponsor: |
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Public title:
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Effect of Surgical Therapy on RANKL/OPG (Osteoprotegerin) System
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Scientific title:
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Effect of Surgical Periodontal Therapy on the RANKL/OPG System : Do we Need Osteo-immune Modulation Targeting RANKL? |
Date of first enrolment:
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January 2010 |
Target sample size:
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65 |
Recruitment status: |
Completed |
URL:
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http://clinicaltrials.gov/show/NCT02190773 |
Study type:
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Observational |
Study design:
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Observational Model: Case Control, Time Perspective: Prospective
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Phase:
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N/A
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Countries of recruitment
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Turkey
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Chronic periodontitis having at least 5mm or more probing depth and aggressive
periodontitis patients.
Exclusion Criteria:
- Any known systemic disorder, used antibiotics and/or anti-inflammatory medications,
had periodontal treatment in the last 3 months and all of them were non smokers.
Subjects who were lactating and pregnant were also excluded.
Age minimum:
18 Years
Age maximum:
70 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Gingival Crevicular Fluid
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RANKL/OPG Ratio
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Aggressive Periodontitis
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Chronic Periodontitis
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Primary Outcome(s)
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RANKL (pmol) level in GCF
[Time Frame: Baseline-3 months]
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OPG level (pg) in GCF
[Time Frame: Baseline-3 months]
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RANKL/OPG ratio
[Time Frame: Baseline - 3months]
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Secondary Outcome(s)
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Il-10 (pg) levels in GCF
[Time Frame: Baseline-3 months]
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IL-1ß (pg) levels in GCF
[Time Frame: Baseline, 3 months after treatment]
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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