Mannitol Improves Cerebral Oxygen Saturation

• Register: ClinicalTrials.gov
• Last refreshed on: 19 February 2015
• Main ID: NCT02091180
• Date of registration: 15/03/2014
• Prospective Registration: No
• Primary sponsor: Dammam University
• Public title: Mannitol Improves Cerebral Oxygen Saturation
• Scientific title: Effect of Preoperative Mannitol Infusion on Cerebral Oxygen Saturation and Patients' Recovery After Laparoscopic Cholecystectomy
• Date of first enrolment: January 2013
• Target sample size: 40
• Recruitment status: Completed
• URL: http://clinicaltrials.gov/show/NCT02091180
• Study type: Interventional
• Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
• Phase: Phase 4

Countries of recruitment

Saudi Arabia

Contacts

• Name: Hany A Mowafi, MD
• Affiliation: University of Dammam

Key inclusion & exclusion criteria

Inclusion Criteria:

- American Society of Anesthesiologists physical status I or II

- aged between 25 and 50 years

- with a body mass index (BMI) 22-34 kg/m2

Exclusion Criteria:

- obstructive or restrictive pulmonary disease

- cardiac dysfunction



Age minimum: 25 Years
Age maximum: 50 Years
Gender: Both

Health Condition(s) or Problem(s) studied

Anesthesia

Intervention(s)

Drug: Mannitol

Drug: Control

Primary Outcome(s)

rSO2 [Time Frame: participants will be followed for the duration of surgery, an expected average of 1 hour]

Secondary Outcome(s)

extubation time [Time Frame: intraoperative]

Secondary ID(s)

2012069

Source(s) of Monetary Support

Please refer to primary and secondary sponsors