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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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8 February 2016 |
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Main ID: |
NCT01715688 |
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Date of registration:
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25/10/2012 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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Efficacy of Alkalinized Lidocaine in the Endotracheal Tube Cuff on the Incidence of Coughing During Emergence
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Scientific title:
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Efficacy of Endotracheal Tube Cuffs Pre-filled With Alkalinized Lidocaine Compared to Endotracheal Tube Cuffs Filled With Saline on the Incidence of Coughing During Emergence of Anesthesia. |
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Date of first enrolment:
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January 2013 |
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Target sample size:
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200 |
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Recruitment status: |
Completed |
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URL:
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https://clinicaltrials.gov/show/NCT01715688 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Prevention
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Phase:
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N/A
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Countries of recruitment
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Canada
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Contacts
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Name:
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Nathalie Massicotte, MD, FRCPC |
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Address:
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Telephone:
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Email:
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Affiliation:
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Centre Hospitalier de l'Université de Monrtréal |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Patients undergoing elective short-duration surgery under general anesthesia
(expected duration of less than 2 hours)
- Physical status 1-3
Exclusion Criteria:
- Asthma or severe pulmonary disease
- Pulmonary tract infection
- Anticipated difficult intubation
- Current use of cough medicine
- Contraindication to lidocaine
- Pregnancy
- Airway surgery
- Inability to provide informed consent
- Patient refusal
Age minimum:
18 Years
Age maximum:
N/A
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Anesthesia
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Cough
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Intervention(s)
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Drug: Saline
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Drug: Alkalinized lidocaine
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Primary Outcome(s)
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Incidence of coughing during emergence of general anesthesia
[Time Frame: At extubation (Day 0)]
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Secondary Outcome(s)
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Incidence of sore throat
[Time Frame: One hour after extubation (Day 0)]
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Time to emergence
[Time Frame: At extubation (Day 0)]
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Secondary ID(s)
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NM2012-003
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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