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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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19 February 2015 |
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Main ID: |
NCT01702779 |
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Date of registration:
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24/04/2012 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Nasal Humidified High Flow Oxygen During Weaning From Mechanical Ventilation : Ultrasonography Study
HiFloLUS |
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Scientific title:
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Date of first enrolment:
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August 2011 |
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Target sample size:
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80 |
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT01702779 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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Phase:
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N/A
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Countries of recruitment
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France
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Contacts
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Name:
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Sébastien PERBET |
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Address:
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Telephone:
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Email:
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Affiliation:
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University Hospital, Clermont-Ferrand |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Adult patients ventilated more than 48 h
- Stable respiratory and hemodynamic conditions for SBT
- Consent of patients
- Arterial line
Exclusion Criteria:
- COBP
- Laryngeal dyspnea
- Tracheostomy
- Arythmya
- No echogenicity
- Paraplegia >T8
Age minimum:
18 Years
Age maximum:
N/A
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Adult Patients Ventilated More Than 48 h
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Stable Respiratory and Hemodynamic Conditions for SBT
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Consent of Patients
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Arterial Line
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Intervention(s)
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Other: mechanical ventilation
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Primary Outcome(s)
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variations of lung ultrasound score
[Time Frame: 24 hours after extubation]
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Secondary Outcome(s)
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Epithelial and endothelial biomarkers
[Time Frame: at baseline, 4-6 hours after extubation, 24 hours after extubation, 48 hours after extubation]
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Lung ultrasound score
[Time Frame: at baseline, 4-6 hours after extubation, 24 hours after extubation, 48 hours after extubation]
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rates of patients with postextubation distress
[Time Frame: during the 48th post-extubation]
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Electrical Impedance tomography
[Time Frame: at baseline, 4-6 hours after extubation, 24 hours after extubation, 48 hours after extubation]
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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