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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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16 December 2017 |
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Main ID: |
NCT01445847 |
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Date of registration:
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29/09/2011 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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The Effect of Intravenous Lidocaine on Post-extubation Laryngospasm
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Scientific title:
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Effect of Intravenous Lidocaine on the Incidence of Post-extubation Laryngospasm: A Randomised Controlled Trial |
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Date of first enrolment:
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January 2012 |
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Target sample size:
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134 |
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Recruitment status: |
Terminated |
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URL:
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https://clinicaltrials.gov/show/NCT01445847 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Prevention. Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor).
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Phase:
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N/A
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Countries of recruitment
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Saudi Arabia
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Contacts
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Name:
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Khalid I Aljonaieh, Lecturer |
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Address:
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Telephone:
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Email:
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Affiliation:
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King Saud University |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- American Society of Anesthesia score are I or II
- Undergo for laparoscopic cholecystectomy
Exclusion Criteria:
- Patient's refusal
- History of upper respiratory tract infection (URTI) within 2 weeks
- Persistent type of hyper-reactive airway or asthma
- History of airway surgery
- History of gastro-esophageal reflex disease (GERD)
- Currently receiving sedating or analgesic medication
- Currently receiving the following medications:
- Fluvoxamine
- Erythromycin and Itraconazole
- ß -blocker or Cimetidine
- History of Lidocaine Allergy
- History of epilepsy disorder
- Pregnant or breastfeeding women
- History of Heavy Smoking ( a smoker with a daily cigarettes consumption of more than
20 pieces
- History of increased salivation by a disease or medication
- History of difficult intubation
- Two or more attempts of intubation
Age minimum:
18 Years
Age maximum:
60 Years
Gender:
All
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Health Condition(s) or Problem(s) studied
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Laryngospasm
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Intervention(s)
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Drug: Lidocaine
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Other: Placebo
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Primary Outcome(s)
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Number of Patients With Laryngospasm Postoperatively
[Time Frame: within first 15 minutes post-dose]
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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