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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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19 February 2015 |
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Main ID: |
NCT01359774 |
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Date of registration:
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23/05/2011 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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31P-MRS and Huntington Disease
PRO-MH |
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Scientific title:
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31Phosphorus-Magnetic Resonance Spectroscopy and Huntington Disease |
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Date of first enrolment:
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April 2011 |
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Target sample size:
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30 |
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT01359774 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
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Phase:
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N/A
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Countries of recruitment
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France
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Contacts
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Name:
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Fanny Mochel, MD, PhD |
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Address:
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Telephone:
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Email:
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Affiliation:
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INSERM UMR S975 Institut du Cerveau et de la Moelle, AP-HP Département de Génétique, Université Pierre et Marie Curie, Paris France |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- 5
- Age>18 years
- Ability to undergo MR scanning
- Covered by french social security
Exclusion Criteria:
- Evidence of psychiatric disorder
- Attendant neurological disorder
- Contraindications to MRI (claustrophobia, metallic or material implants)
- Severe head injury
- Unable to understand the protocol
- Pregnancy
- Failure to give informed consent
- Subjects with exclusion criteria required by french law (e.g. subjects who require a
legally authorized representative to obtain consent)
- Unwillingness to be informed in case of abnormal MRI
Age minimum:
18 Years
Age maximum:
N/A
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Huntington Disease
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Intervention(s)
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Other: 31P-RMN spectroscopy
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Other: 31P-MR spectroscopy
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Primary Outcome(s)
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Brain energy deficit in Huntington patients
[Time Frame: one year]
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Secondary Outcome(s)
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Correlating a brain energy deficit with (i) biochemical parameters and (ii) clinical parameters in Huntington patients
[Time Frame: one year]
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Secondary ID(s)
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C10-56
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2011-A00137-34
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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