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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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19 February 2015 |
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Main ID: |
NCT01349387 |
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Date of registration:
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03/05/2011 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Effect of Treatment With Metformin in Type 2 Diabetes Patients on Alternative Genes Splicing
METFORGENE |
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Scientific title:
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Effect of Treatment With Metformin in Type 2 Diabetes Patients on Alternative Genes Splicing Whose Maturation Depends on the Protein HuR, Including Gene Encoding Insulin Receptor |
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Date of first enrolment:
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May 2011 |
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Target sample size:
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25 |
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT01349387 |
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Study type:
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Interventional |
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Study design:
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Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science
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Phase:
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N/A
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Countries of recruitment
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France
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Contacts
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Name:
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Guillaume CHARPENTIER, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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CHSF-CERITD |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Type 2 Diabetic patients usually treated with metformin (= 1400 mg/day), associated
or not to other oral anti-diabetic treatment or. injection treatment
- Patients major.
- Patients with a social security number
- Patients having signed a consent to participate in the study
Exclusion Criteria:
- Intolerance metformin
- Patients with type 1.
- Patients on pioglitazone or rosiglitazone
- Renal failure by an anomaly of the creatinine clearance (< 60 mL/min).
- Patients pregnant or likely to be.
Age minimum:
18 Years
Age maximum:
N/A
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Type 2 Diabetes
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Intervention(s)
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Drug: Metformin
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Primary Outcome(s)
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Comparison of expression of isoforms A and B of the insulin receptor using quantitative RT PCR
[Time Frame: inclusion (baseline), 30th days and 60th days]
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Secondary ID(s)
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2010-A01389-30
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2011-000128-13
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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