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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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19 February 2015 |
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Main ID: |
NCT01232244 |
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Date of registration:
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01/11/2010 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Oxyntomodulin, Mechanisms of Action in Relation to Appetite, Food Intake, Gastric Emptying and Energy Expenditure.
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Scientific title:
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Date of first enrolment:
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October 2010 |
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Target sample size:
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15 |
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT01232244 |
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Study type:
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Observational |
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Study design:
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N/A
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Phase:
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N/A
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Countries of recruitment
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Denmark
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Contacts
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Name:
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Jonatan I Bagger, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Gentofte University Hospital, University of Copenhagen |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Normal fasting plasma glucose
- Normal glucose tolerance
- Normal haemoglobin levels
- Informed content
Exclusion Criteria:
- Diabetes
- Pre diabetes (impaired glucose tolerance or impaired fasting glucose)
- 1st degree relatives with diabetes
- Obesity (BMI > 30)
- Inflammatory bowels disease
- Bowels surgery
- Nephropathy
- Liver disease
- Medication which cannot be on hold for 24h
Age minimum:
18 Years
Age maximum:
70 Years
Gender:
Male
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Health Condition(s) or Problem(s) studied
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Obesity
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Incretin Action
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Intervention(s)
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Other: GLP-1 infusion
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Other: Oxyntomodulin infusion
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Other: Placebo
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Other: Glucagon infusion
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Other: GLP-1 and glucagon infusion
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Primary Outcome(s)
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Satiety
[Time Frame: 4 h]
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basal energy expenditure
[Time Frame: 2 x 30min]
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Hunger
[Time Frame: 4 h]
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Gastric emptying
[Time Frame: 4 h]
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Secondary Outcome(s)
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Glucagon
[Time Frame: 4 h]
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GLP-1
[Time Frame: 4 h]
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GIP
[Time Frame: 4 h]
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Oxyntomodulin
[Time Frame: 4 h]
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Secondary ID(s)
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OXMDissek
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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