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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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19 February 2015 |
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Main ID: |
NCT00932087 |
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Date of registration:
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22/06/2009 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Characterization of Low Density Lipoprotein and Mechanism of the Pro Aggregant Effect Through Oxidant Stress and Lipid Exchange
ECLIPSE |
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Scientific title:
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Characterization of Low Density Lipoprotein and Mechanism of the Pro Aggregant Effect Through Oxidant Stress and Lipid Exchange |
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Date of first enrolment:
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February 2009 |
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Target sample size:
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48 |
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT00932087 |
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Study type:
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Observational |
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Study design:
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Observational Model: Case Control, Time Perspective: Prospective
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Phase:
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N/A
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Countries of recruitment
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France
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Contacts
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Name:
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Philippe MOULIN, MD, PhD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Hospices Civils de Lyon |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- statin and fibrate Wash out for one week
- HbA1c>7% and <12% (Arms 1 and 3)
- HbA1c<6% (Arms 2 and 4)
- Metabolic sd according NCEP III (3 out 4 criteria) (Arms 1 and 2)
Exclusion Criteria:
- secondary CV prevention
Age minimum:
30 Years
Age maximum:
75 Years
Gender:
Male
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Health Condition(s) or Problem(s) studied
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Diabetes
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Metabolic Syndrome
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Intervention(s)
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Procedure: Blood sample
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Primary Outcome(s)
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Level of plasma isoprostane and lipoperoxides
[Time Frame: at baseline]
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Secondary Outcome(s)
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TXA2 and PF4 levels after platelet activation of control platelet exposed to LDL
[Time Frame: 2 hours]
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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