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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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19 February 2015 |
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Main ID: |
NCT00917345 |
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Date of registration:
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08/06/2009 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Diagnosis of Primary Aldosteronism: Comparison of Post Captopril Active Renin Concentration and Plasma Renin Activity
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Scientific title:
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Date of first enrolment:
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January 2008 |
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Target sample size:
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150 |
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Recruitment status: |
Recruiting |
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URL:
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http://clinicaltrials.gov/show/NCT00917345 |
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Study type:
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Observational |
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Study design:
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Observational Model: Case Control, Time Perspective: Prospective
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Phase:
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N/A
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Countries of recruitment
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Taiwan
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Contacts
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Name:
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VinCent Wu, MD |
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Address:
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Telephone:
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+886927223278 |
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Email:
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q91421028@ntu.edu.tw |
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Affiliation:
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Name:
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VinCent Wu, MD |
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Address:
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Telephone:
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+886937223278 |
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Email:
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion Criteria:
1. age at onset younger than 35 years,
2. hypertension that is difficult to control after initiating therapy,
3. clinical occurrence of a hypertensive crisis,
4. the presence of hypokaliemia or metabolic alkalosis, or a random aldosterone-renin
ration (ARR) >30, and
5. evidence of adrenal incidentaloma and hypertension or hypokalemia.
Exclusion Criteria:
1. chronic kidney disease with elevated estimated glomerular filtration rate (< 60,
mL/min/1.73 m2)
2. liver disease with elevated GPT (> 35)
3. heart failure
4. classified as more than NYHA II,
5. hyperthyroidism
6. malignancy with metastasis
Age minimum:
18 Years
Age maximum:
80 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Primary Aldosteronism
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Intervention(s)
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Drug: captopril test
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Primary Outcome(s)
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Determination of ARC in contrast to PRA offers advantage with regard to processing and standardization, knowing the postcaptopril sensitivity and specificity
[Time Frame: 1 day]
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Secondary ID(s)
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200904076R
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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