1-deamino 8-d-arginine Vasopressin (DDAVP) in Percutaneous Ultrasound-guided Renal Biopsy

• Register: ClinicalTrials.gov
• Last refreshed on: 19 October 2017
• Main ID: NCT00748072
• Date of registration: 05/09/2008
• Prospective Registration: No
• Primary sponsor: University of Bari
• Public title: 1-deamino 8-d-arginine Vasopressin (DDAVP) in Percutaneous Ultrasound-guided Renal Biopsy
• Scientific title: 1-deamino 8-d-arginine Vasopressin in Percutaneous Ultrasound-guided Renal Biopsy: a Randomized Controlled Trial
• Date of first enrolment: August 2008
• Target sample size: 162
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT00748072
• Study type: Interventional
• Phase: Phase 4

Countries of recruitment

Italy

Contacts

• Name: Carlo Manno, MD
• Affiliation: University of Bari

Key inclusion & exclusion criteria

Inclusion Criteria:

1. Males or females > 16 and < 80 years of age.

2. Blood pressure < 140/90 mmHg.

3. Serum creatinine = 1.5 mg/dl and/or creatinine clearance = 60 ml/min.

4. Bleeding time, prothrombin time, partial thromboplastin time, platelets and fibrinogen
in the normal range.

Exclusion Criteria:

1. Biopsy of transplant kidney

2. Poorly controlled hypertension

3. Single kidney

4. Renal cancer

5. Hydro/pyonephrosis

6. Renal size significantly reduced

7. Severe obesity

8. Coagulation disorder

9. Serum creatinine > 1.5 mg/dl and/or creatinine clearance < 60 ml/min



Age minimum: 16 Years
Age maximum: 80 Years
Gender: All

Health Condition(s) or Problem(s) studied

Kidney Failure

Intervention(s)

Drug: DDAVP

Drug: saline solution

Primary Outcome(s)

The Primary Outcome Measure Was the Incidence of Post-biopsy Bleeding Complications. [Time Frame: Immediately post-biopsy and 24 hours post-biopsy.]

Secondary ID(s)

DDAVP 01

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Results

• Results available: Yes
• Date Posted: 13/01/2015
• URL: https://clinicaltrials.gov/ct2/show/results/NCT00748072