Effects of Sea Buckthorn Oil on Dry Eye

• Register: ClinicalTrials.gov
• Last refreshed on: 12 December 2020
• Main ID: NCT00739713
• Date of registration: 21/08/2008
• Prospective Registration: Yes
• Primary sponsor: University of Turku
• Public title: Effects of Sea Buckthorn Oil on Dry Eye DESB
• Scientific title: Effects of Sea Buckthorn Oil on Dry Eye
• Date of first enrolment: September 2008
• Target sample size: 100
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT00739713
• Study type: Interventional
• Study design: Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor).
• Phase: N/A

Countries of recruitment

Finland

Contacts

• Name: Heikki P Kallio, Professor
• Affiliation: University of Turku

Key inclusion & exclusion criteria

Inclusion Criteria:

- Dry eye symptoms

Exclusion Criteria:

- Severe illness

- Anticholinergic drugs

- Smoking



Age minimum: 20 Years
Age maximum: 75 Years
Gender: All

Health Condition(s) or Problem(s) studied

Dry Eye Syndromes

Intervention(s)

Dietary Supplement: Placebo comparison

Dietary Supplement: Sea buckthorn (Hippophaë rhamnoides) oil

Primary Outcome(s)

Symptom severity: symptom questionnaires and clinical dry eye tests [Time Frame: 3 months intervention + 1 month after the intervention]

Secondary Outcome(s)

Tear film lipid profile, tear cytokines, inflammation mediators in blood [Time Frame: 3 months intervention + 1 month after the intervention]

Secondary ID(s)

DESB

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Secondary Sponsor(s)

Turku University Hospital

Finnsusp Ltd.

Valioravinto Ltd

Aromtech Ltd.

Shiny Horse Ltd

The Finnish Funding Agency for Technology and Innovation (TEKES)

Turku Municipal Health Department/evo-funding