Outcome of Embryo Culture at Two Oxygen Tensions

• Register: ClinicalTrials.gov
• Last refreshed on: 19 February 2015
• Main ID: NCT00718822
• Date of registration: 17/07/2008
• Prospective Registration: No
• Primary sponsor: University Clinical Centre, Maribor
• Public title: Outcome of Embryo Culture at Two Oxygen Tensions
• Scientific title: Does Reduced Oxygen Tension in Embryo Culture Influence Clinical Outcome of ICSI Cycles? A Prospective Randomized Trial
• Date of first enrolment: August 2006
• Target sample size: 647
• Recruitment status: Completed
• URL: http://clinicaltrials.gov/show/NCT00718822
• Study type: Interventional
• Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
• Phase: N/A

Countries of recruitment

Slovenia

Contacts

• Name: Veljko Vlaisavljevic, Prof.
• Affiliation: University Clinical Centre, Maribor

Key inclusion & exclusion criteria

Inclusion Criteria:

- stimulated Intra Cytoplasmic Sperm Injection (ICSI) cycle

Exclusion Criteria:

- less than one mature (metaphase II) oocyte at the time of denudation



Age minimum: 22 Years
Age maximum: 44 Years
Gender: Female

Health Condition(s) or Problem(s) studied

Embryo Development

Intervention(s)

Other: oxygen concentration in the culture atmosphere

Primary Outcome(s)

Ongoing pregnancy rate per cycle [Time Frame: 10-11 weeks after embryo transfer]

Secondary Outcome(s)

clinical pregnancy rate, implantation rate, early pregnancy loss, fertilization rate, embryo quality [Time Frame: Yes]

Secondary ID(s)

P3-0327

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Secondary Sponsor(s)

Slovenian Research Agency