Elimination of Protein-bound Uremic Retention Solutes by Prometheus Artificial Hepatic System Versus Conventional Dialysis

• Register: ClinicalTrials.gov
• Last refreshed on: 12 July 2021
• Main ID: NCT00262353
• Date of registration: 04/12/2005
• Prospective Registration: No
• Primary sponsor: University Hospital, Ghent
• Public title: Elimination of Protein-bound Uremic Retention Solutes by Prometheus Artificial Hepatic System Versus Conventional Dialysis
• Scientific title: Elimination of Protein-bound Uremic Retention Solutes by Prometheus Artificial Hepatic System Versus Conventional Dialysis
• Date of first enrolment: May 8, 2003
• Target sample size: 0
• Recruitment status: Withdrawn
• URL: https://clinicaltrials.gov/show/NCT00262353
• Study type: Interventional
• Study design: Allocation: Randomized. Intervention model: Crossover Assignment. Primary purpose: Treatment. Masking: None (Open Label).
• Phase: N/A

Countries of recruitment

Belgium

Contacts

• Name: Raymond Vanholder, MD, PhD
• Affiliation: University Hospital, Ghent

Key inclusion & exclusion criteria

Inclusion Criteria:

- Stable patients

- At least 3 months on dialysis

- Arterio-venous fistula

Exclusion Criteria:

- Diabetic patients

- Malignancies

- Acute illnesses



Age minimum: 18 Years
Age maximum: N/A
Gender: All

Health Condition(s) or Problem(s) studied

Renal Failure, Chronic

Intervention(s)

Device: Dialysis with different artificial devices

Primary Outcome(s)

Determination of the concentration of protein-bound toxins after treatment with different artificial devices

Secondary Outcome(s)

Determination of the kinetics of protein-bound toxins after treatment with different artificial devices

Secondary ID(s)

2004/416

Source(s) of Monetary Support

Please refer to primary and secondary sponsors