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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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JPRN |
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Last refreshed on:
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17 October 2023 |
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Main ID: |
JPRN-UMIN000007417 |
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Date of registration:
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01/03/2012 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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The Esophageal Dysfunction Plays a Key Role in the Pathogenesis of PPI-resistant Globus sensation
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Scientific title:
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The Esophageal Dysfunction Plays a Key Role in the Pathogenesis of PPI-resistant Globus sensation - PPI-resistant Globus sensation |
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Date of first enrolment:
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2011/02/01 |
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Target sample size:
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100 |
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Recruitment status: |
Recruiting |
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URL:
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https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000006270 |
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Study type:
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Interventional |
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Study design:
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Single arm Non-randomized
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Phase:
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Not selected
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Countries of recruitment
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Japan
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Contacts
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Name:
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Address:
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577, Matsushima, Kurashiki, 701-0192
Japan |
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Telephone:
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Email:
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Affiliation:
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Kawasaki Medical School Division of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine |
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Name:
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Manabe Noriaki |
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Address:
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577, Matsushima, Kurashiki, 701-0192
Japan |
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Telephone:
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Email:
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Affiliation:
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Kawasaki Medical School Division of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine |
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Key inclusion & exclusion criteria
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Inclusion criteria:
Exclusion criteria: All patients underwent both larygoscopy and upper gastrointestinal endoscopy to exclude organic disease.
Age minimum:
20years-old
Age maximum:
90years-old
Gender:
Male and Female
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Health Condition(s) or Problem(s) studied
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dyspahgia and/or globus sensation
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Intervention(s)
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After 4 weeks of treatment with rabeprazole sodium (20 mg daily), the patients were divided into PPI-responsive and PPI-resistant groups. Then we investigated oesophageal motility in the PPI-resistant group by a multichannel intraluminal impedance and manometry study.
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Primary Outcome(s)
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The subjects werepatients with globus sensation. All patients underwent both larygoscopy and upper gastrointestinal endoscopy to exclude organic disease. After 4 weeks of treatment with rabeprazole sodium (20 mg daily), the patients were divided into PPI-responsive and PPI-resistant groups. Then we investigated oesophageal motility in the PPI-resistant group by a multichannel intraluminal impedance and manometry study.
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Source(s) of Monetary Support
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Kawasaki Medical School
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Ethics review
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Status: YES
Approval date:
Contact:
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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