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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ISRCTN |
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Last refreshed on:
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13 January 2015 |
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Main ID: |
ISRCTN69559777 |
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Date of registration:
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29/05/2008 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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The ACROSS-China trial
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Scientific title:
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Abnormal gluCose Regulation in patients with acute strOke acroSS China: a national multicentre prospective study |
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Date of first enrolment:
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01/01/2008 |
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Target sample size:
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4000 |
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Recruitment status: |
Completed |
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URL:
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http://isrctn.com/ISRCTN69559777 |
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Study type:
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Observational |
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Study design:
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Multicentre observational, prospective, cohort study (Diagnostic)
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Phase:
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Countries of recruitment
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China
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Contacts
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Name:
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Address:
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Telephone:
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Email:
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Affiliation:
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Name:
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Yongjun
Wang |
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Address:
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Beijing Tiantan Hospital
Tiantan Xili 6
Chongwen District
100050
Beijing
China |
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Telephone:
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Email:
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: 1. Older than 18, either sex
2. Acute stroke: diagnosed on World Health Organization (WHO) criteria
3. Acute primary stroke patients within 14 days
Exclusion criteria: 1. Cerebral infarction without symptoms and signs
2. Non-cerebrovascular events
3. Stroke patients out of 14 days
4. Without the content of patients or their legal agents
Age minimum:
Age maximum:
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Abnormal glucose regulation, acute stroke
Circulatory System
Acute stroke
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Intervention(s)
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All participants without a history of diabetes mellitus will be identified as having abnormal glucose regulation or not by using the oral glucose tolerance test (OGTT) three days before discharge. The outcome and recurrence of stroke will be compared between the patients with and without abnormal glucose regulation respectively at three months and one year after the onset of stroke as below:
1. Modified Rankin Scale (mRS)
2. The times of stroke recurrence
The current therapy measures of abnormal glucose regulation in patients with acute stroke will be observed during in-hospital and follow-up.
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Primary Outcome(s)
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The prevalence of abnormal glucose regulation after acute stroke in China, measured by OGTT before discharge.
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Secondary Outcome(s)
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1. The distribution of stroke subtypes is different in the subtypes of the abnormal glucose regulation
2. The outcome and recurrence risk of stroke in patients with or without abnormal glucose regulation
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Secondary ID(s)
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ACROSS-protocol 5
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Source(s) of Monetary Support
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Bayer (China) Limited, 11th Five-year National Supporting Schedule of Science and Technology (China)
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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