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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ISRCTN |
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Last refreshed on:
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13 January 2015 |
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Main ID: |
ISRCTN47655040 |
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Date of registration:
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30/09/2005 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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The analgesic effect of parecoxib following total abdominal hysterectomy
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Scientific title:
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Date of first enrolment:
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15/05/2002 |
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Target sample size:
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42 |
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Recruitment status: |
Completed |
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URL:
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http://isrctn.com/ISRCTN47655040 |
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Study type:
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Interventional |
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Study design:
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Randomised controlled trial (Not Specified)
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Phase:
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Countries of recruitment
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United Kingdom
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Contacts
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Name:
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Address:
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Telephone:
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Email:
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Affiliation:
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Name:
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A
Ng |
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Address:
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University Hospitals of Leicester
University Hospitals of Leicester
c/o Research and Development Office
Leicester General Hospital NHS Trust
LE1 4PW
Leicester
United Kingdom |
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Email:
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: 1. Patients having total abdominal hysterectomy
2. American Society of Anesthesiologists (ASA) 1-11
3. Aged 20 - 65, female
Exclusion criteria: 1. Patients having hysterectomy/morphine consumption
2. Pain
3. Sedation
4. Nausea
Age minimum:
Age maximum:
Gender:
Female
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Health Condition(s) or Problem(s) studied
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Post-operative pain
Signs and Symptoms
Post-operative pain
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Intervention(s)
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All patients were given intraoperative:
1. Propofol 2 - 4 mg kg intravenously (i.v.)
2. Morphine 10 mg i.v.
3. Prochlorperazine 12.5 mg intramuscularly (i.m.)
Patients' lungs were ventilated with nitrous oxide and isoflurane 1 - 1.5% in oxygen, and morphine was self-administered for postoperative analgesia via a patient controlled analgesia (PCA) device.
Patients were allocated randomly to receive either parecoxib 40 mg i.v. or normal saline on induction of anaesthesia.
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Primary Outcome(s)
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1. Morphine consumption
2. Pain
3. Sedation
4. Nausea
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Secondary Outcome(s)
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Not provided at time of registration
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Secondary ID(s)
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N0123138268
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Source(s) of Monetary Support
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University Hospitals of Leicester NHS Trust (UK), Departmental funding
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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