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Register:	ISRCTN
Last refreshed on:	13 January 2015
Main ID:	ISRCTN46492332
Date of registration:	12/09/2003
Prospective Registration:	No
Primary sponsor:	Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)
Public title:	A randomised controlled study of N-Acetylcysteine in liver transplantation
Scientific title:
Date of first enrolment:	06/09/2001
Target sample size:	170
Recruitment status:	Completed
URL:	http://isrctn.com/ISRCTN46492332
Study type:	Interventional
Study design:	Randomised controlled trial (Not Specified)
Phase:

Countries of recruitment
United Kingdom

Contacts

Name:	Christopher Watson
Address:	Honorary Consultant Surgeon University Department of Surgery Box 202 Addenbrooke's Hospital CB2 2QQ Cambridge United Kingdom
Telephone:	+44 (0)1223 336980
Email:	cjew2@cam.ac.uk
Affiliation:

Name:
Address:
Telephone:
Email:
Affiliation:

Key inclusion & exclusion criteria

Inclusion criteria: Added May 2008:
Adult patients (=18years) undergoing liver transplant

Exclusion criteria: Added May 2008:
Allergy to n-acetyl cysteine

Age minimum:
Age maximum:
Gender: Not Specified

Health Condition(s) or Problem(s) studied

Surgery: Liver transplant
Surgery
Liver transplant

Intervention(s)

Patients undergoing liver transplantation will be randomly allocated to the N-Acetylcysteine group or a control group (no treatment).
Treatment will commence during the liver transplant and continue for 5 days post-operatively. Blood tests and liver biopsies will be taken during the study for analysis.

Primary Outcome(s)

Not provided at time of registration

Secondary Outcome(s)

Not provided at time of registration

Secondary ID(s)

N0544103857

Source(s) of Monetary Support

Cambridge Consortium - Addenbrooke's (UK)

Secondary Sponsor(s)

Ethics review

Results

Results available:
Date Posted:
Date Completed:
URL:

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