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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ISRCTN |
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Last refreshed on:
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17 October 2016 |
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Main ID: |
ISRCTN14121394 |
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Date of registration:
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03/07/2012 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Clinical Assessment Study of the HAnd (CASHA) - 6-year follow-up
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Scientific title:
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The course of hand pain, hand problems and hand osteoarthritis in community-dwelling adults aged 50 years and over: the 6-year follow-up of the Clinical Assessment Study of the Hand (CASHA) |
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Date of first enrolment:
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26/09/2011 |
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Target sample size:
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475 |
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Recruitment status: |
Completed |
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URL:
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http://isrctn.com/ISRCTN14121394 |
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Study type:
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Observational |
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Study design:
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Non-randomised observational cohort study (Screening)
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Phase:
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Not Applicable
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Countries of recruitment
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United Kingdom
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Contacts
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Name:
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Address:
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Telephone:
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Email:
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Affiliation:
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Name:
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George
Peat |
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Address:
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Primary Care Musculoskeletal Research Centre
Keele University
Keele Road
Staffordshire
ST5 5BG
Newcastle-under-Lyme
United Kingdom |
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Telephone:
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- |
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Email:
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g.m.peat@cphc.keele.ac.uk |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: 1. Existing member of the CAS-HA cohort
2. Responded to the 3-year Follow-up Health Questionnaire
3. Provided written informed consent to further contact at 3-year follow-up stage
4. Male & female participants
5. Lower Age Limit 50 years
Exclusion criteria: 1. Participants who have died since 3-year follow-up
2. Participants who have become vulnerable (e.g. participants with known new-onset dementia, serious/terminal pathology) since their baseline assessment as judged by the lead GP at each practice
3. Participants who have withdrawn consent to further contact following the 3-year follow-up
We are keen to avoid upsetting or burdening participants and their relatives whose circumstances may have changed. Prior to any contacts being made for 6-year follow-up we will check to ensure that the mailing list contains no participants who have died. This means checking the mailing list at each practice. We are also including a screen of the mailing list by the lead GP at each practice to identify and exclude those participants who have become vulnerable since the screen was last conducted.
Age minimum:
Age maximum:
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Musculoskeletal, All Diseases
Musculoskeletal Diseases
Polyarthrosis, unspecified
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Intervention(s)
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Seven plain x-rays will be taken of the hands and knees as follows: dorsi-palmar views of each hand and wrist, weight-bearing semiflexed posteroanterior (PA) view of both knees, and lateral and skyline views of each knee in a supine position with the knee flexed to 45 degrees.
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Primary Outcome(s)
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Australian Canadian Hand Osteoarthritis Index (AUSCAN) measured at baseline
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Secondary Outcome(s)
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1. Anxiety and depression (HADS) measured at baseline
2. Current employment status measured at baseline
3. General health (SF-12) measured at baseline
4. Pain location (manikin) measured at baseline
5. Presence of hand pain and problems nodes, swelling, and participation restriction measured at baseline
6. Radiographic hand osteoarthrits (OA) measured at baseline
7. Radiographic knee OA measured at baseline
8. Symptom satisfaction measured at baseline
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Source(s) of Monetary Support
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Arthritis Research (UK)
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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