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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ISRCTN |
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Last refreshed on:
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30 October 2017 |
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Main ID: |
ISRCTN05282752 |
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Date of registration:
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30/11/2005 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Effect of valdecoxib pretreatment on pain and secondary hyperalgesia associated with the heat/capsaicin model in healthy volunteers
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Scientific title:
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Effect of valdecoxib pretreatment on pain and secondary hyperalgesia associated with the heat/capsaicin model in healthy volunteers |
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Date of first enrolment:
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01/01/2004 |
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Target sample size:
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40 |
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Recruitment status: |
Completed |
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URL:
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http://isrctn.com/ISRCTN05282752 |
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Study type:
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Interventional |
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Study design:
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Prospective, double blind, randomized, cross-over (Treatment)
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Phase:
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Not Applicable
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Countries of recruitment
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United States of America
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Contacts
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Name:
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Address:
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Telephone:
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Email:
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Affiliation:
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Name:
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Piotr
Janicki |
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Address:
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Penn State Hershey Medical Ctr
Dept. Anesthesiology
H187
500 University Drive
PA 17036
Hershey
United States of America |
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Telephone:
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- |
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Email:
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pjanicki@psu.edu |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: Healthy volunteers, both genders
Exclusion criteria: Pregnancy, known allergy to COX-2 inhibitors, current infection or treatment with analgesics
Age minimum:
Age maximum:
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Hyperalgesia
Signs and Symptoms
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Intervention(s)
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Administration of single dose 40 mg valdecoxib or placebo orally (PO).
Measurement of heat/cold pain threshold and area of heat/capsaicin-induced hyperalgesia.
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Primary Outcome(s)
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Area of secondary hyperalgesia
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Secondary Outcome(s)
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Pain threshold for cold/heat pain
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Secondary ID(s)
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NCT00260325
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N/A
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Source(s) of Monetary Support
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Independent Investigator Grant from Pfizer Inc.
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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