Clinical observation and the standardization of ultrasound-guided needle knife treatment of the knee osteoarthritis

• Register: ChiCTR
• Last refreshed on: 18 April 2017
• Main ID: ChiCTR-IOR-14005519
• Date of registration: 2014-07-06
• Prospective Registration: Yes
• Primary sponsor: Third Affiliated Hospital of Beijing University of Chinese Medicine
• Public title: Clinical observation and the standardization of ultrasound-guided needle knife treatment of the knee osteoarthritis
• Scientific title: Clinical observation and the standardization of ultrasound-guided needle knife treatment of the knee osteoarthritis
• Date of first enrolment: 2014-12-29
• Target sample size: experimental group :72;control group:72;
• Recruitment status: Pending
• URL: http://www.chictr.org.cn/showproj.aspx?proj=9892
• Study type: Interventional study
• Study design: Randomized parallel controlled trial
• Phase: Other

Countries of recruitment

China

Contacts

• Name: MA Yufeng
• Affiliation: Third Affiliated Hospital of Beijing University of Chinese Medicine

• Name: WANG Qingfu

Key inclusion & exclusion criteria

Inclusion criteria: 1. according to the diagnostic criteria for the knee osteoarthritis;
2. according to the purpose of clinical trials to determine the age range of subjects aged 40 -70 years old;
3. VAS score: VAS more than at leat 4;
4. X line Kellgren-Lawrence classification in patients with stage I-III.
Exclusion criteria: 1. associated with severe cardiovascular patients (such as myocardial infarction, heart failure, severe heart failure), lungs (pulmonary insufficiency such as etc.), liver, kidney, hematopoietic system diseases;
2. the incidence of those affected joints, such as psoriasis, syphilitic neuropathy, ochronosis, metabolic bone disease, acute trauma;
3. the other suffering from rheumatoid arthritis, gouty arthritis and other non-degenerative knee arthritis who;
4. breastfeeding or pregnant women who have a mental illness;
5. 2 weeks received other knee osteoarthritis drug treatment;
6. 1 weeks received anticoagulant therapy;
7. suffering from a knee injury and ulceration of the skin, such as not OK knife treatment;
8. the researchers believe that other reasons were not suitable for clinical trials.

Age minimum: 40
Age maximum: 70
Gender: Both

Health Condition(s) or Problem(s) studied

knee osteoarthritis

Intervention(s)

experimental group :ultrasound-guided therapy;control group:needle knife therapy ;

Primary Outcome(s)

Visual Analogue Scale;

Secondary Outcome(s)

Lysholm Score;

Source(s) of Monetary Support

The Beijing municipal science and technology plan projects