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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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TCTR |
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Last refreshed on:
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1 April 2024 |
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Main ID: |
TCTR20150228001 |
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Date of registration:
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28/02/2015 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Blood Pressure Lowering and Platelet Inhibitory Effects of Juices from Pachyrhizus erosus L. root and Psidium guajava L. fruit: a Control Study in Healthy Volunteers.
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Scientific title:
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Blood Pressure Lowering and Platelet Inhibitory Effects of Juices from Pachyrhizus erosus L. root and Psidium guajava L. fruit: a Control Study in Healthy Volunteers. |
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Date of first enrolment:
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01/03/2011 |
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Target sample size:
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Recruitment status: |
Completed |
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URL:
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https://www.thaiclinicaltrials.org/show/TCTR20150228001 |
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Study type:
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Interventional |
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Study design:
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Randomized
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Phase:
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Phase 1
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Countries of recruitment
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Thailand
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Contacts
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Name:
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Supeenun
Unchern |
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Address:
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272 Rama VI Road, Ratchathewi
10400
Bangkok
Thailand |
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Telephone:
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662-2015641 |
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Email:
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supeenun.unc@mahidol.ac.th |
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Affiliation:
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Lecturer/Investigator |
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Name:
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Supeenun
Unchern |
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Address:
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272 Rama VI Road, Ratchathewi
10400
Bangkok
Thailand |
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Telephone:
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662-2015641 |
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Email:
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supeenun.unc@mahidol.ac.th |
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Affiliation:
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Lecturer/Investigator |
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Key inclusion & exclusion criteria
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Inclusion criteria: 1. Age between 20 to 45 years.
2. Body mass index (BMI) of 18-27 kg per square meter.
Exclusion criteria: 1. History of any serious illnesses, including infectious diseases, cardiovascular and pulmonary diseases.
2. Smoking and/or alcoholic drinking.
3. Systemic medication (other than the oral contraceptive pill).
4. Pregnancy.
Age minimum:
20 Years
Age maximum:
45 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Cardiovascular problems including hypertension and platelet hyperactivity.
Yam been root juice
Guava fruit juice
Circulating nitrate
Circulating nitrite
Blood pressure lowering effect
Platelet inhibitory effect
Plasma cGMP
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Yam been root juice
Guava fruit juice
Circulating nitrate
Circulating nitrite
Blood pressure lowering effect
Platelet inhibitory effect
Plasma cGMP
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Intervention(s)
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Placebo Comparator No treatment,Experimental Dietary Supplement,Experimental Dietary Supplement
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Nitrate-free water,Yam bean root juice,Guava fruit juice
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Control treatment,Yam bean root juice,Guava fruit juice
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Primary Outcome(s)
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Blood pressure and heart rate 0, 0.5, 1, 1.5, 2, 2.5, 3, 5 hours Blood pressure and heart rate monitoring
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Secondary Outcome(s)
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Platelet function 0, 2.5, 5 ours Platelet aggregation assessment
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Source(s) of Monetary Support
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The Thailand Research Fund (TRF)
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Ethics review
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Status:
Approval date:
Contact:
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Results
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Results available:
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Date Posted:
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Date Completed:
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17/12/2013 |
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URL:
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