LED therapy in muscle fatigue

• Register: REBEC
• Last refreshed on: 29 May 2023
• Main ID: RBR-4253s4
• Date of registration: 13/03/2015
• Prospective Registration: No
• Primary sponsor: Universidade Camilo Castelo Branco
• Public title: LED therapy in muscle fatigue
• Scientific title: LED therapy in muscle fatigue
• Date of first enrolment: 10/05/2013
• Recruitment status: Recruitment completed
• URL: http://ensaiosclinicos.gov.br/rg/RBR-4253s4
• Study type: Intervention
• Study design: Randomized, controlled efectiveness trial, parallel, double-blind, with two arms.
• Phase: N/A

Countries of recruitment

Brazil

Contacts

• Name: Antonio Balbin Villaverde
• Affiliation: Universidade Camilo Castelo Branco

• Name: Areolino Pena Matos
• Affiliation: Universidade Camilo Castelo Branco

Key inclusion & exclusion criteria

Inclusion criteria: Women between 60 and 70 years of age; non-athletes; with BMI between 18.5 and 29.99 Kg/m2 who agreed to take part in the approved study after signing the consent form.
Exclusion criteria: Previous lower limb and cervical surgery; degenerative systemic diseases; regular use of muscle relaxants or use at least 3 days before the test; rhabdomyolysis; neuromuscular disease, myasthenia gravis; polymyositis; asymptomatic degenerative or inflammatory joint disease in the hands, wrists, and elbows; tendinitis or tenosynovitis of the wrist extensors or flexors and fingers.

Age minimum: 60Y
Age maximum: 70Y
Gender: F

Health Condition(s) or Problem(s) studied

G11.427.550

Sarcopenia, Muscle fatigue

C10.597.613.612.500

Intervention(s)

E02.774

Thirty volunteers between 60 and 70 years will participate in a double-blind, placebo-controlled study, randomized in two groups: LED Group (LG; n = 15), the irradiated group will receive phototherapy with a light-emitting diode LED in 638 nm, 150 mW, 4.5 J / point, 18 J total in four equidistant points in the dominant forearm, on the belly of the flexor muscles of the wrist and fingers and Placebo (PG, n = 15), with similar procedures, however in PG a small protective shield will be placed over the tip of the probe, blocking the light. After irradiation, there will be the induction of muscle fatigue by exercise using 75% of one maximum repetition (1MR) previously calculated. Grip strength will be measured by hydraulic dynamometer, number of repetitions of wrist flexion up to fatigue, Creatine Kinase (CK) levels will be measured by blood samples collected from the ventral surface of the non-dominant arm (5 ml) for experienced and blind nurse before and after 1, 5, 10 and 15 min post muscle fatigue induction.

Other

Primary Outcome(s)

Increase or maintenance of muscle grip strength; measured by hydraulic dynamometry in group treated with LED, verified by at least 1 kg force strength variation, before and after muscle fatigue induction

Secondary Outcome(s)

Secondary outcomes are not expected.

Source(s) of Monetary Support

Universidade Camilo Castelo Branco

Secondary Sponsor(s)

Areolino Pena Matos