Comparison of the anaesthetic effects of 4% articaine hydrochloride and 2% lidocaine hydrochloride for maxillary molar extraction: A randomised trial

• Register: PACTR
• Last refreshed on: 29 May 2023
• Main ID: PACTR201802003023333
• Date of registration: 27/01/2018
• Prospective Registration: No
• Primary sponsor: Dr Adigun Olufemi Ibraheem
• Public title: Comparison of the anaesthetic effects of 4% articaine hydrochloride and 2% lidocaine hydrochloride for maxillary molar extraction: A randomised trial
• Scientific title: Comparison of the anaesthetic effects of 4% articaine hydrochloride and 2% lidocaine hydrochloride for maxillary molar extraction: A randomised double blind crossover study.
• Date of first enrolment: 05/01/2015
• Target sample size: 14
• Recruitment status: Recruiting
• URL: https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=3023
• Study type: Interventional
• Study design: Crossover: all participants receive all interventions in different sequence during study,Randomised,Simple randomisation using by using procedures such as coin-tossing or dice-rolling,Allocation was determined by the holder of the sequence who is situated off site
• Phase: Not Applicable

Countries of recruitment

Nigeria

Contacts

• Name: Oladimeji Akadiri
• Affiliation: Supervisor

• Name: Chibuzo Uguru
• Affiliation: Supervisor

Key inclusion & exclusion criteria

Inclusion criteria: 1 Patients that require bilateral extraction of corresponding firm maxillary molar teeth.
Acute pulpitis
Chronic pulpitis.
Acute exacerbation of chronic apical periodontitis.
Pre-orthodontic extraction.
Chronic apical periodontitis.
2 Patients that are between the ages of 18 and 40 years.
3 Patients that require simple, intra-alveolar extraction only.
4 Consenting patients.
5 Fully erupted teeth.

Exclusion criteria: 1 Presence of underlying systemic diseases such as hypertension, diabetes, blood dyscrasias etc.
2 Non consenting patients.
3 Extractions that end in root fracture.
4 Impacted teeth.
5 Presence of inflammatory conditions such as dentoalveolar abscess.
6 Patients on medication that can interfere with local anaesthetic agents such as meperidine, phenytoin, quinidine and cimetidine.
7 Chronic alcoholic patients


Age minimum: 18 Year(s)
Age maximum: 40 Year(s)
Gender: Both

Health Condition(s) or Problem(s) studied

Compairing two types of local anaesthetic agents on pain control during dental extractions.

Anaesthesia

Oral Health
Compairing two types of local anaesthetic agents on pain control during dental extractions.
Anaesthesia

Oral Health

Intervention(s)

Extraction of upper molar tooth using LIDOCAINE

Extraction of upper molar tooth using ARTICAINE

Primary Outcome(s)

Effectiveness of anaesthesia is recorded based on patients' score of the level of pain experienced during extraction exercise for each side of jaw and pain level in buccal and palatal gingival sulci 10 minutes after buccal infiltration usin visual analog scale chart recording.

To determine and compare the effectiveness of buccal infiltrations in anaesthesizing palatal nerve during extraction of upper molars. Using both articaine and lidocaine as anaesthetic agents.

Secondary Outcome(s)

To determine and compare complications of articaine with lidocainne during upper molar extractions

To determine and compare onset of action of articaine with lidocaine during extraction of maxillary molaes

Source(s) of Monetary Support

Dr Adigun Olufemi Ibraheem

Secondary Sponsor(s)

Dr Akadiri Oladimeji A.

Dr Uguru Chibuzo C.

Ethics review

Status: Approved
Approval date: 28/01/2014
Contact:

University of Nigeria Teaching Hospital Health Research Ethics Committee.