Efficacy study of the consumption of milk fortified in vitamins and minerals

• Register: PACTR
• Last refreshed on: 29 May 2023
• Main ID: PACTR201410000896410
• Date of registration: 29/09/2014
• Prospective Registration: No
• Primary sponsor: Ibn Tofail University
• Public title: Efficacy study of the consumption of milk fortified in vitamins and minerals
• Scientific title: Efficiency study of iodine fortification of milk on iodine status markers: A longitudinal interventional non randomized, controlled study among school children in Morocco
• Date of first enrolment: 01/02/2012
• Target sample size: 200
• Recruitment status: Other
• URL: https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=896
• Study type: Interventional
• Study design: Parallel: different groups receive different interventions at same time during study,Non-randomised,Numbered containers
• Phase: Not Applicable

Countries of recruitment

Morocco

Contacts

• Name: Hassan Aguenaou

• Name: Hassan AGUENAOU
• Affiliation: Ibn Tofail University

Key inclusion & exclusion criteria

Inclusion criteria: To be included in the study, children had to be aged between 7 and 9 years and should not take supplements during the study period
Exclusion criteria: Children with severe malnutrition needing nutritional rehabilitation, or having chronic or severe illness requiring hospitalization or treatment were excluded from the study

Age minimum: 7 Year(s)
Age maximum: 9 Year(s)
Gender: Both

Health Condition(s) or Problem(s) studied

Micronutrient deficiencies

Micronutrient deficiencies

Intervention(s)

Efficiency study of multiple micronutrients fortification of milk on nutritional status

Primary Outcome(s)

Results of the fortified group showed that the prevalence of iron deficiency anemia (IDA) dropped from 1.8% at baseline to 0% at endline and prevalence of iron deficiency (ID) dropped significantly from 50.9% to 37.2% (p=0.037) compared to the non-fortified group where prevalences remained stable for both IDA and ID.

Data analysis clearly demonstrated the amelioration of iodine status in fortified and non-fortified milk groups. Severe and mild iodine deficiencies were reduced for both groups. Moreover, there¿s complete disappearance of severe deficient cases in the fortified milk group after 4 months of intervention.

The prevalence of vitamin A deficiency for the fortified group dropped from 50% at baseline to 4.3% at end line compared to non-fortified group where it dropped from 44% to 24.8%. The difference between both groups was highly significant (p<0.0001).

Secondary Outcome(s)

ongoing

Source(s) of Monetary Support

Ibn Tofail University

Ethics review

Status: Approved
Approval date: 01/02/2012
Contact:

General secretariat of the ministry of education