Topical Minoxidil Versus Topical Glyceryl Trinitrate in Treatment of Chronic Anal Fissure

• Register: ClinicalTrials.gov
• Last refreshed on: 12 December 2020
• Main ID: NCT03528772
• Date of registration: 06/05/2018
• Prospective Registration: Yes
• Primary sponsor: Mansoura University
• Public title: Topical Minoxidil Versus Topical Glyceryl Trinitrate in Treatment of Chronic Anal Fissure
• Scientific title: Topical 5% Minoxidil Versus 0.2%Topical Glyceryl Trinitrate in Treatment of Chronic Anal Fissure: a Randomized Controlled Trial
• Date of first enrolment: May 10, 2018
• Target sample size: 62
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT03528772
• Study type: Interventional
• Study design: Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: Triple (Participant, Investigator, Outcomes Assessor).
• Phase: N/A

Countries of recruitment

Egypt

Contacts

• Name: Sameh Emile, M.D.
• Affiliation: Mansoura University

Key inclusion & exclusion criteria

Inclusion Criteria:

- Patients of both genders presenting with chronic anal fissure of more than 6 weeks in
duration

- Ageing between 18 and 65 years old.

Exclusion Criteria:

- Pregnant patients.

- Patients with recurrent anal fissure after previous sphincterotomy.

- Patients with coexisting anorectal diseases or inflammatory bowel diseases.



Age minimum: 18 Years
Age maximum: 65 Years
Gender: All

Health Condition(s) or Problem(s) studied

Anal Fissure

Intervention(s)

Drug: Minoxidil

Drug: Glyceryl trinitrate

Primary Outcome(s)

Healing duration [Time Frame: two months]

Secondary Outcome(s)

Anal pain [Time Frame: three months]

Secondary ID(s)

mansoura50

Source(s) of Monetary Support

Please refer to primary and secondary sponsors