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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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12 December 2020 |
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Main ID: |
NCT03501459 |
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Date of registration:
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10/04/2018 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Lymphocyte Markers As Predictors Of Responsiveness To Rituximab Among Patients With Idiopathic Nephrotic Syndrome
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Scientific title:
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Lymphocyte Markers As Predictors Of Responsiveness To Rituximab Among Patients With Idiopathic Nephrotic Syndrome |
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Date of first enrolment:
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June 2008 |
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Target sample size:
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100 |
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Recruitment status: |
Recruiting |
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URL:
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https://clinicaltrials.gov/show/NCT03501459 |
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Study type:
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Interventional |
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Study design:
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Allocation: N/A. Intervention model: Single Group Assignment. Primary purpose: Treatment. Masking: None (Open Label).
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Phase:
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Phase 3
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Countries of recruitment
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Singapore
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Contacts
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Name:
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Hui-Kim Yap |
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Address:
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Telephone:
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Email:
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hui_kim_yap@nuhs.edu.sg |
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Affiliation:
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Name:
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Hui-Kim Yap |
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Address:
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Telephone:
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Email:
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hui_kim_yap@nuhs.edu.sg |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Age 1-18 years old at the time of diagnosis of nephrotic syndrome
- Steroid-dependent (SDNS) or steroid-resistant nephrotic syndrome (SDNS)
Exclusion Criteria:
- eGFR <60 ml/min per 1.73m2
- infantile onset of nephrotic syndrome
- nephrotic syndrome secondary to chronic infections such as hepatitis B, hepatitis C or
human immunodeficiency virus, systemic lupus erythematosus, Henoch-Schönlein purpura,
IgA nephropathy, membranoproliferative glomerulonephritis or membranous nephropathy
- current or previous therapy for tuberculosis
- presence of mutations in WT1, NPHS1, NPHS2 and TRPC6.
Age minimum:
1 Year
Age maximum:
N/A
Gender:
All
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Health Condition(s) or Problem(s) studied
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Nephrotic Syndrome
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Intervention(s)
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Drug: Rituximab
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Primary Outcome(s)
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Response
[Time Frame: 3 months]
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Secondary ID(s)
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NMRC/NIG/0026/2008
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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