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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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12 December 2020 |
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Main ID: |
NCT03491163 |
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Date of registration:
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29/03/2018 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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Evaluation of Damaging Factors to Endothelial Glycocalyx During Heart Surgery Pilot Study
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Scientific title:
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Evaluation of Damaging Factors to Endothelial Glycocalyx During On-pump Coronary Artery Bypass Surgery |
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Date of first enrolment:
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March 29, 2018 |
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Target sample size:
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150 |
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Recruitment status: |
Unknown status |
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URL:
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https://clinicaltrials.gov/show/NCT03491163 |
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Study type:
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Observational |
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Study design:
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Phase:
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Countries of recruitment
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Lithuania
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Contacts
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Name:
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Tadas Cesnaitis |
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Address:
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Telephone:
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+37037326171 |
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Email:
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tadas.cesnaitis@lsmuni.lt |
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Affiliation:
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Name:
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Tadas Cesnaitis, MD |
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Address:
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Telephone:
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+37037326171 |
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Email:
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tadas.cesnaitis@lsmuni.lt |
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Affiliation:
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Name:
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Edmundas Sirvinskas, Prof |
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Address:
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Telephone:
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Email:
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Affiliation:
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Professor at Lithuanian University of Health Sciences |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Elective on-pump coronary artery bypass surgery needed.
- Normal heart function at the time of operation.
- Patients without infections.
- Patients who signed study informed consent form
Exclusion Criteria:
- Life saving operation.
- Renal or hepatic dysfunction.
- Off-pump heart operation.
Age minimum:
18 Years
Age maximum:
N/A
Gender:
All
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Health Condition(s) or Problem(s) studied
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Heart; Surgery, Heart, Functional Disturbance as Result
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Intervention(s)
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Diagnostic Test: Syndecan-1 concentration evaluation
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Primary Outcome(s)
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Changes of syndecan-1 concentration during surgery and postoperative period.
[Time Frame: 2 years]
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The correlation of inflammatory status with glycocalyx damage.
[Time Frame: 2 years]
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Assess the risk of early postoperative complications and find possible correlation to syndecan-1 concentration changes.
[Time Frame: 2 years]
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Glycocalyx damage to patients with diabetes vs non-diabetes during heart surgery.
[Time Frame: 2 years]
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The evaluation of aortic clamping and on-pump duration on endothelial glycocalyx damage using syndecan-1 concentration measure.
[Time Frame: 2 years]
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Secondary ID(s)
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ENDOTEL SYNDECAN-1
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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