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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.

Register:	ClinicalTrials.gov
Last refreshed on:	12 December 2020
Main ID:	NCT03467074
Date of registration:	06/03/2018
Prospective Registration:	No
Primary sponsor:	University Hospital, Basel, Switzerland
Public title:	Role of Interferon-? and Vaccine Response
Scientific title:	Association of Genetic Polymorphisms in the Interferon-? Signaling Cascade and Immune Response After Vaccination
Date of first enrolment:	September 1, 2014
Target sample size:	200
Recruitment status:	Completed
URL:	https://clinicaltrials.gov/show/NCT03467074
Study type:	Observational
Study design:
Phase:

Countries of recruitment
Switzerland

Contacts

Name:	Adrian Egli, PD MD
Address:
Telephone:
Email:
Affiliation:	Department of Clinical Microbiology

Key inclusion & exclusion criteria

Inclusion Criteria:

- held allogeneic stem cell transplantation over 1 year ago

Exclusion Criteria:

- Known vaccine intolerance (e.g. Protein allergy or severe vaccine-associated side
effects, e.g. Guillian Barré syndrome)

Age minimum: 18 Years
Age maximum: N/A
Gender: All

Health Condition(s) or Problem(s) studied

Vaccine Response Impaired

Allogeneic Stem Cell Transplantation

Intervention(s)

Biological: influenza A/B vaccine

Primary Outcome(s)

Peripheral Blood Mononuclear Cells (PBMCs) in blood before vaccination [Time Frame: Change from baseline PBMCs at day 60]

Peripheral Blood Mononuclear Cells (PBMCs) in blood after vaccination [Time Frame: Change from baseline PBMCs at day 60]

Secondary Outcome(s)

Secondary ID(s)

2014-141; me15Egli

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Secondary Sponsor(s)

Ethics review

Results

Results available:
Date Posted:
Date Completed:
URL:

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