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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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12 December 2020 |
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Main ID: |
NCT03410576 |
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Date of registration:
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06/01/2018 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Perioperative Time Course of MMP-9 and Its Inhibitor During Carotid Artery Stenting and Carotid Endarterectomy
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Scientific title:
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Comparison of the Perioperative Time Course of Matrix Metalloproteinase-9 (MMP-9) and Its Inhibitor (TIMP-1) During Carotid Artery Stenting (CAS) and Carotid Endarterectomy (CEA) |
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Date of first enrolment:
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October 1, 2013 |
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Target sample size:
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25 |
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Recruitment status: |
Completed |
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URL:
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https://clinicaltrials.gov/show/NCT03410576 |
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Study type:
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Observational |
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Study design:
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Phase:
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Countries of recruitment
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Hungary
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Contacts
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Name:
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Gábor Woth, MD, PhD |
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Address:
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Email:
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Affiliation:
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Department of Anaesthesiology and Intensive Therapy, Medical School, University of Pécs |
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Name:
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Lajos Bogár, MD, DsC |
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Address:
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Email:
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Affiliation:
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Department of Anaesthesiology and Intensive Therapy, Medical School, University of Pécs |
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Name:
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Diana Mühl, MD, PhD |
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Address:
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Email:
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Affiliation:
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Department of Anaesthesiology and Intensive Therapy, Medical School, University of Pécs |
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Name:
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Ferenc Kövér, MD |
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Address:
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Email:
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Affiliation:
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Department of Neurosurgery, Medical School, University of Pécs, |
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Name:
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Bálint Nagy, MD, PhD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Department of Anaesthesiology and Intensive Therapy, Medical School, University of Pécs |
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Name:
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János Lantos, PhD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Department of Surgical Research and Techniques, Medical School, University of Pécs, |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
elective carotid artery surgery
Exclusion Criteria:
Malignant diseases, inflammatory and systemic autoimmune disorders, psychiatric disorders
and previous debilitating stroke
Age minimum:
18 Years
Age maximum:
N/A
Gender:
All
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Health Condition(s) or Problem(s) studied
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Ischemia Reperfusion Injury
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Carotid Stenosis
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Intervention(s)
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Procedure: Carotid artery stenting
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Procedure: Carotid endarterectomy
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Primary Outcome(s)
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Plasma MMP-9 concentrations
[Time Frame: 4 days]
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Plasma TIMP-1 concentrations
[Time Frame: 4 days]
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Secondary Outcome(s)
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MMP-9/TIMP-1 ratio
[Time Frame: 4 days]
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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