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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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16 December 2017 |
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Main ID: |
NCT03270280 |
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Date of registration:
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29/08/2017 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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Comparison of Salivary Interleukin-1ß and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis
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Scientific title:
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Comparison of Salivary Interleukin-1ß and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis Before and After Treatment With Nigella Sativa (Kalonji) Oil |
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Date of first enrolment:
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September 11, 2017 |
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Target sample size:
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25 |
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Recruitment status: |
Not yet recruiting |
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URL:
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https://clinicaltrials.gov/show/NCT03270280 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Health Services Research. Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor).
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Phase:
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Phase 2
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Countries of recruitment
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Pakistan
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Contacts
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Name:
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Ghazala Hassan, MPhil |
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Address:
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Telephone:
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Email:
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Affiliation:
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Research Scholar |
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Name:
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Ghazala Hassan, MPhil |
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Address:
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Telephone:
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+92 320 4635693 |
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Email:
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mashal_18@hotmail.com |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Male and female healthy individual
- Individuals diagnosed with chronic periodontitis according to the WHO criteria.
- Age 19 to 40 years.
Exclusion Criteria:
- Patients with gingivitis only.
- Patients using tobacco products and alcohol.
- Underlying systemic pathology such as diabetes mellitus, cardiovascular disease,
arthritis etc.
- Oral mucosal pre-neoplastic lesions (leukoplakia, erthroplakia, lichen planus) and
oral carcinomas.
- Obese patients.
- Pregnant females.
- Xerostomia.
- Previous history of radiotherapy or chemotherapy.
- Positive history of oral prophylactic procedures (mouthwashes and antibiotics).
- Positive history of any periodontal treatment during last 6 months.
- Positive antibiotic therapy history within last month of study.
Age minimum:
19 Years
Age maximum:
40 Years
Gender:
All
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Health Condition(s) or Problem(s) studied
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Chronic Periodontitis
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Intervention(s)
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Drug: Normal saline
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Drug: Nigella Sativa Oil
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Primary Outcome(s)
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Levels of IL 1-Beta and MMP-8
[Time Frame: 2 weeks]
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Secondary ID(s)
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UniversityHSL
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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