Bispectral Index (BIS) Values Required for an Adequate Depth of Anesthesia in Elderly Patients Using Propofol

• Register: ClinicalTrials.gov
• Last refreshed on: 12 December 2020
• Main ID: NCT03195530
• Date of registration: 20/06/2017
• Prospective Registration: No
• Primary sponsor: Pontificia Universidad Catolica de Chile
• Public title: Bispectral Index (BIS) Values Required for an Adequate Depth of Anesthesia in Elderly Patients Using Propofol
• Scientific title: Bispectral Index (BIS) Values Required for an Adequate Depth of Anesthesia in Elderly Patients Using Propofol, According to the Characteristic Electroencephalographic Pattern
• Date of first enrolment: May 1, 2017
• Target sample size: 12
• Recruitment status: Terminated
• URL: https://clinicaltrials.gov/show/NCT03195530
• Study type: Observational

Countries of recruitment

Chile

Key inclusion & exclusion criteria

Inclusion Criteria:

- Patients over 65 years

- Scheduled for elective surgery requiring general anesthesia

- American Society of Anesthesiology (ASA) Score I or II

Exclusion Criteria:

- Patients with neurological diseases

- Requiring the use of two or more drugs affecting Central nervous system

- History of drugs or alcohol abuse

- Body mass index over 35 kg/m^2

- Propofol allergy

- Cardiac congestive failure

- History of coronary syndrome

- Minimental test altered (Score under 24 points)



Age minimum: 65 Years
Age maximum: N/A
Gender: All

Health Condition(s) or Problem(s) studied

Anesthesia

Intervention(s)

Drug: Propofol

Primary Outcome(s)

BIS values at which EEG patterns (Slow and alpha bands) appears in elderly population using propofol [Time Frame: Induction of anesthesia]

Secondary Outcome(s)

Propofol concentration required to observe specific EEG patterns [Time Frame: Induction of anesthesia]

Secondary ID(s)

161207002

Source(s) of Monetary Support

Please refer to primary and secondary sponsors