Impact of Clinical Pharmacist on Adverse Drug Events in Older Adults

• Register: ClinicalTrials.gov
• Last refreshed on: 16 December 2017
• Main ID: NCT03156348
• Date of registration: 10/05/2017
• Prospective Registration: No
• Primary sponsor: University of Chile
• Public title: Impact of Clinical Pharmacist on Adverse Drug Events in Older Adults
• Scientific title: Impact of Clinical Pharmacist on Post-discharge Prevention of Adverse Drug Events in Older Adults: Randomized Clinical Trial.
• Date of first enrolment: May 2, 2015
• Target sample size: 611
• Recruitment status: Recruiting
• URL: https://clinicaltrials.gov/show/NCT03156348
• Study type: Interventional
• Study design: Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Prevention. Masking: Single (Outcomes Assessor).
• Phase: N/A

Countries of recruitment

Chile

Contacts

• Name: Jorge Hasbun, Dr

• Name: Marcela Jirón, PhD
• Affiliation: University of Chile

Key inclusion & exclusion criteria

Inclusion Criteria:

- Patients attended by the staff of internists of the internal medicine service of the
Clinical Hospital of the University of Chile for acute condition or decompensation of
chronic pathology.

- Patients with an estimated survival of more than 6 months.

- Patients who are on pharmacological therapy.

- Patients who have a contact person or responsible caregiver, willing to comply with
the scheduled care plan.

- Patients who have a contact telephone number

Exclusion Criteria:

- Patients without cognitive autonomy in which it is not possible to establish contact
with the caregiver.

- Any other condition that in the judgment of the research team affects the quality of
the collection of the information.



Age minimum: 60 Years
Age maximum: N/A
Gender: All

Health Condition(s) or Problem(s) studied

Drug-Related Side Effects and Adverse Reactions

Intervention(s)

Other: Clinical Pharmacist Care

Primary Outcome(s)

Incidence of Adverse Drug Events at 90 days post discharge [Time Frame: 90 days post discharge]

Secondary Outcome(s)

Incidence of adverse drug reactions [Time Frame: 90 days post discharge]

Prevalence of self medication in each group [Time Frame: 90 days post discharge]

Characterization of the interventions made by the clinical pharmacist to the health team [Time Frame: 90 days post discharge]

Adherence measured with Morisky & Green Scale [Time Frame: 90 days post discharge]

Incidence of non-programmed/programmed consultations or hospitalizations after discharge from the hospital [Time Frame: 90 days post discharge]

Incidence of potentially inappropriate medication [Time Frame: 90 days post discharge]

Prevalence of Polypharmacy (5 or more drugs) [Time Frame: 90 days post discharge]

Presence of clinically relevant drug interactions [Time Frame: 90 days post discharge]

Secondary ID(s)

SA14ID0141

Source(s) of Monetary Support

Please refer to primary and secondary sponsors