ICTRP Search Portal

Main

Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.

Register:	ClinicalTrials.gov
Last refreshed on:	8 March 2021
Main ID:	NCT03106714
Date of registration:	03/04/2017
Prospective Registration:	Yes
Primary sponsor:	Oswaldo Cruz Foundation
Public title:	Study on the Persistence of Zika Virus (ZIKV) in Body Fluids of Patients With ZIKV Infection in Brazil ZikaBra
Scientific title:	Study on the Persistence of Zika Virus (ZIKV) in Body Fluids of Patients With ZIKV Infection in Brazil
Date of first enrolment:	July 21, 2017
Target sample size:	260
Recruitment status:	Completed
URL:	https://clinicaltrials.gov/show/NCT03106714
Study type:	Observational
Study design:
Phase:

Countries of recruitment
Brazil

Contacts

Name:	Marcus VG Lacerda, MD,PhD
Address:
Telephone:
Email:
Affiliation:	Tropical Medicine Foundation, Manaus

Name:	Guilherme A Calvet, MD,PhD
Address:
Telephone:
Email:
Affiliation:	Oswaldo Cruz Foundation (Evandro Chagas National Institute of Infectious Diseases- Rio de Janeiro)

Name:	Rafael FO França, PhD
Address:
Telephone:
Email:
Affiliation:	Oswaldo Cruz Foundation (Research Centre Aggeu Magalhães- Recife)

Name:	Nathalie JN Broutet, MD, PhD
Address:
Telephone:
Email:
Affiliation:	Department of Reproductive Health and Research World Health Organization

Name:	Ana Maria B de Filippis, PhD
Address:
Telephone:
Email:
Affiliation:	Oswaldo Cruz Foundation (Flavivirus Diagnostic and Reference Laboratory- Rio de Janeiro)

Key inclusion & exclusion criteria

Index Case - Enrolment Inclusion criteria

- RT-PCR test positive for ZIKV in blood and/or urine specimens

- Having given consent to provide all body fluid collection, as per protocol

Exclusion criteria RT-PCR test negative for ZIKV in blood and/or urine specimens

Household contacts enrollment (or sexual contacts if index case lives alone) Inclusion
criteria

- As per index case Exclusion criteria

- As per index case

Age minimum: 18 Years
Age maximum: N/A
Gender: All

Health Condition(s) or Problem(s) studied

Zika Virus

Intervention(s)

Diagnostic Test: RT-PCR

Primary Outcome(s)

Persistence and duration of ZIKV [Time Frame: 12 months of follow-up after ZIKV infection diagnosis]

Secondary Outcome(s)

Secondary ID(s)

TSA2-2017/731359-0

ERC.0002786

R21AI139777

TSA1-2017/720873-0

206522/Z/17/Z

Convênio 837059/2016

W81XWH-18-2-0040

62518016.6.1001.0008

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Secondary Sponsor(s)

World Health Organization

Wellcome Trust

Ministry of Health, Brazil

Walter Reed Army Institute of Research (WRAIR)

National Institute of Allergy and Infectious Diseases (NIAID)

Ethics review

Results

Results available:
Date Posted:
Date Completed:
URL:

Disclaimer: Trials posted on this search portal are not endorsed by WHO, but are provided as a service to our users. In no event shall the World Health Organization be liable for any damages arising from the use of the information linked to in this section. None of the information obtained through use of the search portal should in any way be used in clinical care without consulting a physician or licensed health professional. WHO is not responsible for the accuracy, completeness and/or use made of the content displayed for any trial record.