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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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12 December 2020 |
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Main ID: |
NCT03055715 |
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Date of registration:
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14/02/2017 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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Prognostic Evaluation of Tumor Volume and Its Changes in Radical Radiotherapy of Advanced NSCLC
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Scientific title:
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Multicentric Retrospective Prognostic Evaluation of Tumor Volume and Their Change in the Curative-intended, Radical Radiotherapy of Locally Advanced NSCLC |
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Date of first enrolment:
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April 1, 2017 |
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Target sample size:
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346 |
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Recruitment status: |
Completed |
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URL:
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https://clinicaltrials.gov/show/NCT03055715 |
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Study type:
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Observational |
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Study design:
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Phase:
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Countries of recruitment
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Austria
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Belgium
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Germany
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Spain
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Switzerland
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Contacts
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Name:
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Christian Ostheimer, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Klinik fuer Strahlentherapie, Martin-Luther-Universitaet Halle-Wittenberg |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Histologically confirmed NSCLC (Adeno / SCC) Stage UICC III A or B
- CT based radiation treatment planning (PET- or PET-CT-based if available)
- completed curative-intended radiotherapy ± chemotherapy (achieved total dose = 60 Gy
normofractionated or = 50 Gy hypofractionated)
Exclusion Criteria:
- Stereotactic radiotherapy
- Second malignancy <5 years before diagnosis of NSCLC
- Pleural effusion ipsilateral, extensive atelectasis ipsilateral
Age minimum:
18 Years
Age maximum:
100 Years
Gender:
All
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Health Condition(s) or Problem(s) studied
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Non Small Cell Lung Cancer Stage III
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Primary Outcome(s)
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Overall Survival (months)
[Time Frame: 5 months]
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Secondary Outcome(s)
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Absolute Gross Tumor Volume before Radiation Boost (GTV2)
[Time Frame: 5 months]
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Relative Gross Tumor Volume Changes (delta GTV related to basal GTV)
[Time Frame: 5 months]
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Absolute Basal Gross Tumor Volume (ml) before Radiotherapy (GTV1)
[Time Frame: 5 months]
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Secondary ID(s)
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ARO 2017-1
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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