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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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16 December 2017 |
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Main ID: |
NCT03044561 |
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Date of registration:
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02/02/2017 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Sildenafil Citrate of in Vitro Fertilization After Multiple IVF Failures Attributed to Poor Endometrial Development
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Scientific title:
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Effect of Sildenafil Citrate on the Outcome of in Vitro Fertilization After Multiple IVF Failures Attributed to Poor Endometrial Development |
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Date of first enrolment:
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January 31, 2017 |
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Target sample size:
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80 |
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Recruitment status: |
Recruiting |
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URL:
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https://clinicaltrials.gov/show/NCT03044561 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: None (Open Label).
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Phase:
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Phase 4
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Countries of recruitment
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Egypt
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Contacts
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Name:
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amr elsayed |
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Address:
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Telephone:
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01090808047 |
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Email:
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Affiliation:
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Name:
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ahmed khairy, professor |
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Address:
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Telephone:
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01090808047 |
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Email:
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Affiliation:
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Name:
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ahmed khairy, professor |
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Address:
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Telephone:
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Email:
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Affiliation:
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Ain Shams University |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- (1) cases of infertility, older than 20 years of age and not older than 40 years.
- (2) Body mass index (BMI):20-29.
- (3) women have experienced two or more implantation failure attributed to inadequate
endometrial development.
Exclusion Criteria:
- (1) Uterine abnormalities (e.g. septate, bicornuate and fibroid uterus, Asherman
Syndrome).
- (2) Any contraindication to sildenafil citrate or any of the components of its
formulation including:
- Concurrent use of organic nitrites and nitrates.
- Severe hepatic impairment.
- Severe renal impairment.
- Hypotension.
- Recent stroke or heart attack.
Age minimum:
20 Years
Age maximum:
40 Years
Gender:
Female
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Health Condition(s) or Problem(s) studied
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IVF Failure
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Intervention(s)
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Drug: Sildenafil Citrate
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Drug: matching placebo
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Primary Outcome(s)
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endometrial thickness measures
[Time Frame: 21 days]
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Secondary ID(s)
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amr el-sayed 2017
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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