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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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21 November 2016 |
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Main ID: |
NCT02962700 |
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Date of registration:
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04/11/2016 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Effects of Continuous Haemofiltration vs Intermittent Haemodialysis on Microcirculatory Parameters in Septic Shock
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Scientific title:
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Effects of Continuous Haemofiltration vs Intermittent Haemodialysis on Microcirculatory Parameters in Septic Shock |
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Date of first enrolment:
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January 2016 |
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Target sample size:
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100 |
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Recruitment status: |
Recruiting |
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URL:
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https://clinicaltrials.gov/show/NCT02962700 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Screening
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Phase:
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N/A
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Countries of recruitment
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Tunisia
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Contacts
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Name:
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zied hajjej |
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Address:
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Telephone:
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20358907 |
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Email:
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hajjej_zied@hotmail.com |
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Affiliation:
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Name:
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mustapha ferjani |
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Address:
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Telephone:
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98329256 |
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Email:
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mustapha.ferjani@planet.tn |
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Affiliation:
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Name:
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mustapha ferhjani |
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Address:
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Telephone:
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Email:
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Affiliation:
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Department of C ritical C are Medicine and Anesthesiology, Military Hospital of Tunis, Tunisia, Tunis, Tunisia |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- septic shock
Exclusion Criteria:
Age minimum:
16 Years
Age maximum:
90 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Septic Shock
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Intervention(s)
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Device: muscle microdialysis
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Primary Outcome(s)
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changes in the concentration of pyruvate (µmol/l) in the extracellular fluid of the skeletal muscle using a microdialysis probe inserted into the quadriceps femoris muscle
[Time Frame: at baseline, 6, 12, 18, 24, 30, 36, 42 and 48 hours after initiation of renal replacement]
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changes in the concentration of glucose (mmol/l) in the extracellular fluid of the skeletal muscle using a microdialysis probe inserted into the quadriceps femoris muscle.
[Time Frame: at baseline, 6, 12, 18, 24, 30, 36, 42 and 48 hours after initiation of renal replacement]
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changes in the concentration of glycerol (µmol/l) in the extracellular fluid of the skeletal muscle using a microdialysis probe inserted into the quadriceps femoris muscle
[Time Frame: at baseline, 6, 12,18, 24, 30, 36, 42 and 48 hours after initiation of renal replacement]
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changes in the concentration of lactate (mmol/l) in the extracellular fluid of the skeletal muscle using a microdialysis probe inserted into the quadriceps femoris muscle
[Time Frame: at baseline, 6, 12, 18, 24, 30, 36, 42 and 48 hours after initiation of renal replacement]
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Secondary Outcome(s)
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changes in mean arterial blood pressure
[Time Frame: at baseline, 6, 12, 18, 24, 30, 36, 42 and 48 hours after initiation of renal replacement]
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changes in heart rate
[Time Frame: at baseline, 6, 12, 18, 24, 30, 36, 42 and 48 hours after initiation of renal replacement]
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changes in vasopressor support doses
[Time Frame: at baseline, 6, 12, 18, 24, 30, 36, 42 and 48 hours after initiation of renal replacement]
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Secondary ID(s)
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CVVHFmicro
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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