Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?

• Register: ClinicalTrials.gov
• Last refreshed on: 12 December 2020
• Main ID: NCT02962024
• Date of registration: 07/11/2016
• Prospective Registration: No
• Primary sponsor: Fatma Adel El sherif,MD
• Public title: Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?
• Scientific title: Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block for Post Mastectomy Pain Has a System Analgesic Effect? A Clinical and Pharmacokinetics Study
• Date of first enrolment: November 2016
• Target sample size: 40
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT02962024
• Study type: Interventional
• Study design: Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Health Services Research. Masking: Double (Participant, Investigator).
• Phase: N/A

Countries of recruitment

Egypt

Contacts

• Name: fatma EL sherif
• Affiliation: South Egypt Cancer Instuite, Assuit, Assuit university

Key inclusion & exclusion criteria

Inclusion Criteria:

- (ASA) class I-II

- body weight of 50 - 90 kg

Exclusion Criteria:

- a history of bleeding diathesis,

- relevant drug allergy, opioid dependence,

- sepsis, prior surgery in the supraclavicular, infraclavicular or axillary regions,
alcohol or drug abuse , patients with advanced cardiovascular disease



Age minimum: 18 Years
Age maximum: 60 Years
Gender: Female

Health Condition(s) or Problem(s) studied

Postoperative Complications

Intervention(s)

Drug: Morphine Sulfate

Drug: Bupivacaine Hydrochloride

Primary Outcome(s)

serum morphine level after local injection [Time Frame: 24 hours]

Secondary ID(s)

348

Source(s) of Monetary Support

Please refer to primary and secondary sponsors