Risk Factors for Vascular Calcifications in Hemodialysis Patients: to What Extent is Vitamin K2 Deficiency Involved?

• Register: ClinicalTrials.gov
• Last refreshed on: 26 September 2016
• Main ID: NCT02876354
• Date of registration: 11/08/2016
• Prospective Registration: No
• Primary sponsor: Saint-Joseph University
• Public title: Risk Factors for Vascular Calcifications in Hemodialysis Patients: to What Extent is Vitamin K2 Deficiency Involved?
• Scientific title: Risk Factors for Vascular Calcifications in Hemodialysis Patients: to What Extent is Vitamin K2 Deficiency Involved?
• Date of first enrolment: August 2016
• Target sample size: 50
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT02876354
• Study type: Interventional
• Study design: Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
• Phase: Phase 4

Countries of recruitment

Lebanon

Contacts

• Name: Mabel Aoun, MD
• Affiliation: Université Saint-Joseph, Beirut, Lebanon

Key inclusion & exclusion criteria

Inclusion Criteria:

- Patients on chronic hemodialysis in our center older than 18 years old who sign the
informed consent.

Exclusion Criteria:

- Patients who are not eligible for a discontinuation of vitamin k antagonists



Age minimum: 18 Years
Age maximum: N/A
Gender: Both

Health Condition(s) or Problem(s) studied

Vascular Calcifications

Intervention(s)

Drug: Menaquinone

Primary Outcome(s)

Rate of decrease of dp-ucMGP after daily supplementation with menaquinone [Time Frame: Baseline-Four weeks]

Secondary ID(s)

SGH001

Source(s) of Monetary Support

Please refer to primary and secondary sponsors