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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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12 December 2020 |
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Main ID: |
NCT02864173 |
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Date of registration:
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04/08/2016 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Whole Genome Single Nucleotide Polymorphisms in Elderly Patients With Postoperative Cognitive Dysfunction
GenPOCD |
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Scientific title:
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Whole Genome Single Nucleotide Polymorphisms in Elderly Patients With Postoperative Cognitive Dysfunction |
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Date of first enrolment:
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August 2007 |
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Target sample size:
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63 |
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Recruitment status: |
Completed |
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URL:
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https://clinicaltrials.gov/show/NCT02864173 |
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Study type:
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Observational |
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Study design:
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Phase:
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Countries of recruitment
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Switzerland
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Contacts
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Name:
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Nicolai Goettel, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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University Hospital, Basel, Switzerland |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- American Society of Anesthesiologists (ASA) physical status I-IV
- Major noncardiac surgery under general anesthesia
- Native German or French speakers
Exclusion Criteria:
- Cardiac surgery
- Neurosurgery
- Surgery within 12 months prior to inclusion
- History of intracranial or cerebrovascular pathology
- Preoperative Mini-Mental State Examination (MMSE) score <24
- Psychiatric disease and long-term psychopharmacological treatment
Age minimum:
65 Years
Age maximum:
N/A
Gender:
All
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Health Condition(s) or Problem(s) studied
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Postoperative Cognitive Dysfunction
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Intervention(s)
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Genetic: Whole genome small nucleotide polymorphism genotyping
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Primary Outcome(s)
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Change from baseline in the Consortium to Establish a Registry for Alzheimer's Disease Neuropsychological Assessment Battery (CERAD-NAB) scores at one week
[Time Frame: Postoperative day 7]
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Secondary Outcome(s)
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Mini-Mental State Examination (MMSE)
[Time Frame: Postoperative day 7]
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Trail Making Test Part A
[Time Frame: Postoperative day 7]
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Trail Making Test Part B
[Time Frame: Postoperative day 7]
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Phonemic Fluency Test (S-words)
[Time Frame: Postoperative day 7]
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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