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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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12 December 2020 |
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Main ID: |
NCT02745925 |
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Date of registration:
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18/04/2016 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Mechanism of Decreased Iron Absorption in Obesity: Controlling Adiposity-related Inflammation
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Scientific title:
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Mechanism of Decreased Iron Absorption in Obesity: Controlling Adiposity-related Inflammation |
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Date of first enrolment:
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April 2016 |
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Target sample size:
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40 |
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Recruitment status: |
Completed |
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URL:
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https://clinicaltrials.gov/show/NCT02745925 |
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Study type:
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Interventional |
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Study design:
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Allocation: Non-Randomized. Intervention model: Parallel Assignment. Primary purpose: Basic Science. Masking: None (Open Label).
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Phase:
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N/A
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Countries of recruitment
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Switzerland
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Contacts
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Name:
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Isabelle Herter-Aeberli, PhD |
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Address:
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Telephone:
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Email:
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Affiliation:
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University of Zurich |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- normal-weight (BMI18.5-24.9kg/m2) or obesity (BMI 29-40kg/m2)
- pre-menopausal
- no chronic illness and no significant medical conditions that could influence iron or
inflammatory status other than obesity
- no-smoking
Exclusion Criteria:
- Diagnosed chronic disease or gastrointestinal disorders
- Metabolic disorders (e.g. diabetes)
- Regular use of medication (except oral contraceptives)
- Subject on a weight loss diet or planning to start a weight loss diet during the
duration of the study
- Pregnancy or lactation
Age minimum:
18 Years
Age maximum:
45 Years
Gender:
Female
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Health Condition(s) or Problem(s) studied
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Obesity
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Intervention(s)
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Drug: Ibuprofen
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Primary Outcome(s)
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Fractional iron absorption
[Time Frame: Days 15 and 45]
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Secondary Outcome(s)
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Hemoglobin
[Time Frame: Days 1, 15, 30, 45]
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interleukin-6
[Time Frame: Days 1, 15, 30, 45]
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Hepcidin
[Time Frame: Days 1, 15, 30, 45]
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alpha-1-acid-glycoprotein
[Time Frame: Days 1, 15, 30, 45]
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c-reactive protein
[Time Frame: Days 1, 15, 30, 45]
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Plasma ferritin
[Time Frame: Days 1, 15, 30, 45]
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Transferrin receptor
[Time Frame: Days 1, 15, 30, 45]
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Secondary ID(s)
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Fe_Abs_Ibu
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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