Effect of Spirulina on Liver Iron Concentration in Beta Thalassemic Children With Hepatitis C

• Register: ClinicalTrials.gov
• Last refreshed on: 12 December 2020
• Main ID: NCT02744560
• Date of registration: 16/04/2016
• Prospective Registration: No
• Primary sponsor: Tanta University
• Public title: Effect of Spirulina on Liver Iron Concentration in Beta Thalassemic Children With Hepatitis C
• Scientific title: Effect of Spirulina on Liver Iron Concentration in Beta Thalassemic Children With Hepatitis C
• Date of first enrolment: March 2015
• Target sample size: 30
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT02744560
• Study type: Interventional
• Study design: Allocation: N/A. Intervention model: Single Group Assignment. Primary purpose: Supportive Care. Masking: None (Open Label).
• Phase: N/A

Countries of recruitment

Egypt

Key inclusion & exclusion criteria

Inclusion Criteria:

- multitransfused beta thalassemic children with super added hepatitis C virus (HCV)
infection diagnosed by serological detection of HCV antibodies and HCV RNA by
polymerase chain reaction.

Exclusion Criteria:

- liver decompensation child younger than 3 years patients with hepatitis B infection
contraindications to perform MRI (intraocular metallic foreign body, cardiac
pacemaker, intracranial clips of arterial brain aneurysms) refusal to participate in
the study



Age minimum: 6 Years
Age maximum: 18 Years
Gender: All

Health Condition(s) or Problem(s) studied

Beta Thalassemia Major

Intervention(s)

Dietary Supplement: spirulina

Primary Outcome(s)

liver iron concentration using magnetic resonance imaging (T2* gradient echo pulse sequence in the axial plane) [Time Frame: 3 months]

Secondary ID(s)

3026/01/15

Source(s) of Monetary Support

Please refer to primary and secondary sponsors