Effect of Spirulina on Liver Fibrosis by Transient Elastography in Beta Thalassemic Children With Hepatitis C

• Register: ClinicalTrials.gov
• Last refreshed on: 12 December 2020
• Main ID: NCT02744105
• Date of registration: 16/04/2016
• Prospective Registration: No
• Primary sponsor: Tanta University
• Public title: Effect of Spirulina on Liver Fibrosis by Transient Elastography in Beta Thalassemic Children With Hepatitis C
• Scientific title: Effect of Spirulina on Liver Fibrosis by Transient Elastography in Beta Thalassemic Children With Hepatitis C
• Date of first enrolment: December 2015
• Target sample size: 60
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT02744105
• Study type: Interventional
• Study design: Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Supportive Care. Masking: Double (Care Provider, Outcomes Assessor).
• Phase: N/A

Countries of recruitment

Egypt

Key inclusion & exclusion criteria

Inclusion Criteria:

- multitransfused beta thalassemic children with and without super added hepatitis C
virus (HCV) infection diagnosed by serological detection of HCV antibodies and HCV RNA
by polymerase chain reaction.

Exclusion Criteria:

- liver decompensation child younger than 3 years patients with hepatitis B infection
implantable cardiac device failure to obtain transient elastography (Fibroscan)
results



Age minimum: 6 Years
Age maximum: 18 Years
Gender: All

Health Condition(s) or Problem(s) studied

Beta Thalassemia Major

Intervention(s)

Dietary Supplement: Spirulina

Primary Outcome(s)

liver stiffness measurement using transient elastography (Fibroscan) [Time Frame: 3 months]

Secondary Outcome(s)

liver function tests [Time Frame: 3 months]

aspartate aminotransferase to platelet ratio index (APRI) [Time Frame: 3 months]

Secondary ID(s)

2902/11/14

Source(s) of Monetary Support

Please refer to primary and secondary sponsors