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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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9 January 2017 |
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Main ID: |
NCT02739399 |
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Date of registration:
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06/04/2016 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Effects of Phenylephrine on Cardiac Preload
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Scientific title:
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The Dynamic Effects of Phenylephrine on Preload and Cardiac Output in Patients Under General Anaesthesia |
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Date of first enrolment:
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February 2016 |
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Target sample size:
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26 |
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Recruitment status: |
Completed |
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URL:
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https://clinicaltrials.gov/show/NCT02739399 |
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Study type:
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Interventional |
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Study design:
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Endpoint Classification: Pharmacodynamics Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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Phase:
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Phase 4
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Countries of recruitment
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Belgium
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Contacts
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Name:
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Alain F Kalmar, MD, PhD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Department of Anaesthesiology and Intensive care medicine, Maria Middelares hospital, Ghent, Belgium |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Adult
- necessity for arterial blood pressure monitoring
- necessity for central venous blood pressure monitoring
Exclusion Criteria:
- unwilling or unable to grant written informed consent
- cardiac arrythmia
- contra-indication for phenylephrine
- contra-indications for atropine
- contra-indication for Total Intravenous Anesthesia
Age minimum:
18 Years
Age maximum:
85 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Anaesthesia
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Arterial Hypotension
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Intervention(s)
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Drug: Phenylephrine
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Primary Outcome(s)
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Cardiac output
[Time Frame: perioperative]
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Secondary Outcome(s)
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End-Tidal CO2
[Time Frame: perioperative]
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Arterial Blood Pressure
[Time Frame: perioperative]
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Pulse Pressure Variation
[Time Frame: perioperative]
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central venous pressure
[Time Frame: perioperative]
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Secondary ID(s)
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MM2015.037
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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