Automatic Chlorination and Child Health in Urban Bangladesh

• Register: ClinicalTrials.gov
• Last refreshed on: 16 December 2017
• Main ID: NCT02606981
• Date of registration: 20/10/2015
• Prospective Registration: No
• Primary sponsor: Stanford University
• Public title: Automatic Chlorination and Child Health in Urban Bangladesh
• Scientific title: Evaluating Low-cost Automatic Water Disinfection Systems to Improve Water Quality and Child Health in Urban Bangladesh
• Date of first enrolment: July 2015
• Target sample size: 1549
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT02606981
• Study type: Interventional
• Study design: Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Prevention. Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor).
• Phase: N/A

Countries of recruitment

Bangladesh

Contacts

• Name: Amy Pickering, PhD
• Affiliation: Stanford University

• Name: Stephen Luby, MD
• Affiliation: Stanford University

Key inclusion & exclusion criteria

Inclusion Criteria:

- Households with at least one child under 60 months old

- Households using enrolled shared water point as primary drinking water source

Exclusion Criteria:

- Households with a private drinking water source

Note: New births and children under 60 months that migrate into compounds accessing the
enrolled water points for drinking water will be enrolled into the study.



Age minimum: N/A
Age maximum: 60 Months
Gender: All

Health Condition(s) or Problem(s) studied

Communicable Diseases

Diarrhea

Intervention(s)

Device: Active control, vitamin C dosing into water

Device: Water chlorination by the Flogenic

Primary Outcome(s)

Diarrhea longitudinal prevalence [Time Frame: Measured every 2-3 months for 16 months post baseline]

Secondary Outcome(s)

Respiratory illness longitudinal prevalence [Time Frame: Measured every 2-3 months for 16 months post baseline]

Prevalence and number of enteric pathogens [Time Frame: Measured 6-12 months after intervention delivery among children under five]

C-reactive protein [Time Frame: Measured at baseline and conclusion of study (16 months post baseline) among children under five]

Caregiver defined diarrhea [Time Frame: Measured every 2-3 months for 16 months post baseline]

total immunoglobin G (IgG) [Time Frame: Measured at baseline and conclusion of study (16 months post baseline) among children under five]

Height-for-age-z-score [Time Frame: Measured at baseline and 16 months after baseline]

Weight-for-age-z-score [Time Frame: Measured every 2-3 months for 16 months post baseline]

Secondary ID(s)

30456

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Secondary Sponsor(s)

International Centre for Diarrhoeal Disease Research, Bangladesh