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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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16 December 2017 |
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Main ID: |
NCT02531399 |
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Date of registration:
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20/08/2015 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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Measurement of Total Retinal Blood Flow During Flicker Stimulation in Healthy Subjects
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Scientific title:
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Measurement of Total Retinal Blood Flow During Flicker Stimulation in Healthy Subjects |
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Date of first enrolment:
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October 2015 |
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Target sample size:
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20 |
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Recruitment status: |
Completed |
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URL:
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https://clinicaltrials.gov/show/NCT02531399 |
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Study type:
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Interventional |
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Study design:
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Intervention model: Single Group Assignment. Primary purpose: Basic Science. Masking: None (Open Label).
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Phase:
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N/A
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Countries of recruitment
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Austria
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Contacts
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Name:
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Gerhard Garhoefer, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Department of Clinical Pharmacology, Medical University of Vienna |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Informed consent for participation
- Men and women aged between 18 and 45 years
- Non-smokers
- Normal findings in the medical history and physical examination unless the
investigator considers an abnormality to be clinically irrelevant
- Systolic blood pressure < 140 mmHg, diastolic blood pressure < 90 mmHg
- Normal ophthalmic findings, ametropia less than 3 diopters
Exclusion Criteria:
- History or presence of ocular disease
- Ametropy = 3 dpt
- Treatment with any drug in the 3 weeks preceding the first study day
- Symptoms of a clinically relevant illness in the 3 weeks before the first study day
- Participation in a clinical trial in the 3 weeks preceding the first study day
- Blood donation during the 3 weeks preceding the first study day
- History of family history of epilepsy
- Abuse of alcoholic beverages
- Pregnancy
Age minimum:
18 Years
Age maximum:
45 Years
Gender:
All
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Health Condition(s) or Problem(s) studied
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Healthy
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Intervention(s)
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Device: LSFG
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Device: LDV
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Device: FDOCT
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Device: DVA
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Primary Outcome(s)
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Flicker induced changes in total retinal blood flow (FDOCT)
[Time Frame: 1 day]
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Secondary Outcome(s)
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Retinal oxygen saturation (DVA)
[Time Frame: 1 day]
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Relative Flow Volume (LSFG)
[Time Frame: 1 day]
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Retinal vessel diameters (DVA)
[Time Frame: 1 day]
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Red blood cell velocity (LDV)
[Time Frame: 1 day]
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Secondary ID(s)
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OPHT-250315
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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